Najib Mohamad Ahmad, Izani Noor Jamil Noor, Amilah Wan Abdul Wahab Wan Nor, Faez Arizam Muhamad, Shafizol Zainuddin
School of Health Sciences, Universiti Sains Malaysia, Kelantan, Malaysia.
Faculty of Veterinary Medicine, Universiti Malaysia Kelantan, Kelantan, Malaysia.
Malays J Med Sci. 2020 Feb;27(1):22-36. doi: 10.21315/mjms2020.27.1.3. Epub 2020 Feb 27.
This review aimed to provide a comprehensive overview of ruminant and human fascioliasis in Malaysia and to identify research gaps in knowledge of the prevalence of fascioliasis in Malaysia and risk factors for the disease using available evidence-based data. We conducted a scoping review based on the framework of Arksey and O'Malley. The preferred reporting items for systematic reviews and meta-analyses were used to guide the review process. The citation search was performed between May and September 2018. Using specific keywords, literature published between 1998 to September 2018 was retrieved from electronic databases. Six articles related to fascioliasis in Malaysia were included in the final review from 1,932 screened articles and reports. Five studies focused on ruminants, including cattle, buffaloes, sheep and goats in the states of Terengganu and Perak. The most frequent ruminant fascioliasis outbreaks involved cattle and goats, with a prevalence of 82%-95% and these outbreaks occurred in Terengganu. Only one study examined the risk of fascioliasis in cattle. In the study, the age and sex of the cattle were important risk-related parameters. The search returned only one documented report of a suspected case of human fascioliasis with an atypical clinical presentation. At present, human fascioliasis in Malaysia remains under-reported and its prevalence remains unknown. The data summarised in this review based on existing evidence identifies research gaps on fascioliasis in ruminants and humans.
本综述旨在全面概述马来西亚反刍动物和人类的片形吸虫病，并利用现有循证数据确定马来西亚片形吸虫病患病率及该病危险因素方面的知识研究空白。我们基于阿克西和奥马利的框架进行了一项范围综述。系统评价和荟萃分析的首选报告项目被用于指导综述过程。在2018年5月至9月期间进行了文献检索。使用特定关键词，从电子数据库中检索了1998年至2018年9月发表的文献。在1932篇筛选的文章和报告中，最终纳入了6篇与马来西亚片形吸虫病相关的文章。5项研究聚焦于反刍动物，包括丁加奴州和霹雳州的牛、水牛、绵羊和山羊。最常见的反刍动物片形吸虫病疫情涉及牛和山羊，患病率为82%-95%，这些疫情发生在丁加奴州。只有一项研究调查了牛患片形吸虫病的风险。在该研究中，牛的年龄和性别是重要的风险相关参数。检索结果仅返回一份有记录的疑似人类片形吸虫病非典型临床表现病例报告。目前，马来西亚人类片形吸虫病报告不足，其患病率仍然未知。本综述基于现有证据总结的数据确定了反刍动物和人类片形吸虫病方面的研究空白。
