马来西亚医院来源的侵袭性和非侵袭性B族链球菌多位点序列分型分析
Multilocus Sequence Typing Analysis of Invasive and Non-Invasive Group B Streptococcus of Hospital Origin in Malaysia.
作者信息
Ezhumalai Menagah, Muthanna AbdulRahman, Suhaili Zarizal, Dzaraly Nurul Diana, Amin-Nordin Syafinaz, Amal Mohammad Noor Azmai, Desa Mohd Nasir Mohd
机构信息
Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Selangor, Malaysia.
School of Animal Sciences, Faculty of Bioresources and Food Industry, Universiti Sultan Zainal Abidin, Terengganu, Malaysia.
出版信息
Malays J Med Sci. 2020 Feb;27(1):134-138. doi: 10.21315/mjms2020.27.1.14. Epub 2020 Feb 27.
Abstract
The aim of this study was to study the genotype of a hospital collection of Group B Streptococcus (GBS) from invasive and non-invasive sites. Fifty-one pre-characterised human of GBS were re-identified and further analysed by multilocus sequence typing (MLST) in relation to previously published serotypes. Fifteen sequence types (ST) were found with ST1 being the most predominant. ST1 was also associated with majority of the invasive isolates. The genotypic distribution patterns of GBS in this study were largely in agreement with previous reports from other countries indicating the tendency of certain genotypes to prevail in human infection settings.
摘要
本研究的目的是研究从侵袭性和非侵袭性部位收集的一组医院B族链球菌（GBS）的基因型。对51株预先鉴定的GBS进行重新鉴定，并通过多位点序列分型（MLST）进一步分析，同时与先前公布的血清型进行关联。共发现15种序列类型（ST），其中ST1最为常见。ST1也与大多数侵袭性分离株相关。本研究中GBS的基因型分布模式与其他国家先前的报告基本一致，表明某些基因型在人类感染环境中占优势的趋势。
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