Queen's Centre of Oncology Castle Hill Hospital, Cottingham, United Kingdom.
Bexley Wing, St James University Hospital, Leeds, United Kingdom.
Oncol Res Treat. 2020;43(4):170-174. doi: 10.1159/000505375. Epub 2020 Mar 11.
Hepatoid adenocarcinoma (AC) of the stomach (HAS) represents a rare variant of conventional gastric AC characterised by poor prognosis. They are usually managed with surgery (localised disease) and chemotherapy.
We present the first case report of a patient with HAS who presented with weight loss, poor appetite, general clinical deterioration (performance status [PS] = 3), and active gastrointestinal bleeding who was treated with fractionated palliative radiotherapy (RT) using 30 Gy in 10 fractions. The use of RT was associated with excellent symptomatic and radiological response and facilitated surgery secondary to significant improvement in general fitness and PS.
RT may have a role in the multimodality management of hepatoid AC of the stomach.
胃肝样腺癌 (HAS) 是一种罕见的胃浸润性腺癌变异型，具有预后不良的特点。HAS 通常采用手术（局部疾病）和化疗进行治疗。
我们首次报告了一例 HAS 患者，该患者表现为体重减轻、食欲不振、一般临床恶化（表现状态 [PS] = 3）和活动性胃肠道出血，采用 30 Gy 分 10 次进行姑息性分割放疗 (RT) 治疗。RT 的应用与出色的症状和影像学反应相关，并由于一般健康状况和 PS 显著改善，从而促进了手术。
RT 在胃肝样腺癌的多模态管理中可能具有一定作用。
