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应用黏弹仪诊断和治疗创伤性凝血病。

Diagnosis and Treatment of Trauma-Induced Coagulopathy by Viscoelastography.

机构信息

Haemonetics Corporation, Boston, Massachusetts.

Saint Joseph Regional Medical Center, Mishawaka, Indiana.

出版信息

Semin Thromb Hemost. 2020 Mar;46(2):134-146. doi: 10.1055/s-0040-1702171. Epub 2020 Mar 11.

Abstract

This article explores the application of viscoelastic tests (VETs) in trauma-induced coagulopathy and trauma resuscitation. We describe the advantages of VETs over conventional coagulation tests in the trauma setting and refer to previous disciplines in which VET use has reduced blood product utilization, guided prohemostatic agents, and improved clinical outcomes such as the mortality of critically bleeding patients. We describe different VETs and provide guidance for blood component therapy and prohemostatic therapy based on specific VET parameters. Because the two most commonly used VET systems, rotational thromboelastometry and thromboelastography, use different activators and have different terminologies, this practical narrative review will directly compare and contrast these two VETs to help the clinician easily interpret either and use the interpretation to determine hemostatic integrity in the bleeding trauma patient. Finally, we anticipate the future of new viscoelastic technologies that can be used in this setting.

摘要

本文探讨了黏弹性测试(VETs)在创伤性凝血障碍和创伤复苏中的应用。我们描述了 VET 在创伤环境下优于传统凝血测试的优势,并提到了以前的学科,其中 VET 的使用减少了血液制品的使用,指导了促凝剂,并改善了临床结果,如严重出血患者的死亡率。我们描述了不同的 VET,并根据特定的 VET 参数提供了血液成分治疗和促凝治疗的指导。由于最常用的两种 VET 系统,旋转血栓弹性测定法和血栓弹性描记法,使用不同的激活剂和具有不同的术语,本实用叙述性综述将直接比较和对比这两种 VET,以帮助临床医生轻松解释任何一种,并使用解释来确定出血创伤患者的止血完整性。最后,我们预计未来可以在这种情况下使用新的黏弹性技术。

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