Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Semin Thromb Hemost. 2020 Mar;46(2):147-154. doi: 10.1055/s-0040-1702203. Epub 2020 Mar 11.
Trauma-induced coagulopathy (TIC) is well documented in injured children. However, many important features of pediatric hemostasis are still in development in early childhood and may impact TIC. Certain pediatric subgroups are at a higher risk. Traumatic brain injury, which occurs with a higher rate in children, and physical child abuse are known risk factors for TIC that deserve special consideration. Resuscitation of a pediatric trauma patient follows many of the same goals as in the injured adult trauma, although some key aspects of pediatric resuscitation require ongoing investigation. Venous thromboembolism occurs with higher rates in certain high-risk groups of pediatric trauma patients, although overall it is considerably less frequent in children as compared with adults.
创伤性凝血病(TIC)在受伤儿童中已有充分记录。然而,儿童止血的许多重要特征仍处于早期发育阶段,可能会影响 TIC。某些儿科亚组的风险更高。创伤性脑损伤在儿童中发生率更高,身体虐待是 TIC 的已知危险因素,值得特别关注。儿科创伤患者的复苏与成人创伤患者的复苏目标大致相同,尽管儿科复苏的某些关键方面仍需要进一步研究。静脉血栓栓塞在某些儿科创伤高危患者中的发生率较高,尽管与成人相比,儿童中的发生率要低得多。