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主动脉球囊阻断在全主动脉弓置换术中的应用与冷冻象鼻技术在主动脉夹层患者临床终点的比较。

Application of Aortic Balloon Occlusion in Total Aortic Arch Replacement with Frozen Elephant Trunk on Clinical Endpoints for Aortic Dissection Patients.

机构信息

Aortic and Vascular Surgery Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

出版信息

Ann Thorac Cardiovasc Surg. 2020 Dec 20;26(6):332-341. doi: 10.5761/atcs.oa.19-00288. Epub 2020 Mar 11.

Abstract

PURPOSE

Total aortic arch replacement (TAR) with frozen elephant trunk (FET) is the standard operation for treating aortic dissection (AD) patients involving aortic arch with high operative risk due to long circulatory arrest (CA). We used aortic balloon occlusion technique that safely reduced the CA time to 5 min in average and investigated whether it can improve the clinical endpoints.

METHODS

All patients diagnosed with AD and underwent TAR with FET operation (123 with aortic balloon occlusion and 221 with conventional method) in Fuwai Hospital during August 2017 and February 2019 was reviewed in this retrospective observational study.

RESULTS

After propensity score matching, the 30-day mortality of aortic balloon occlusion group and conventional group was 4.88% and 11.38% (P = 0.062), respectively. In multivariate analysis, aortic balloon occlusion is one of the factors that reduced the risk for renal and hepatic injury, shortened postoperative conscious revival time, and reduced red blood cell (RBC) transfusion during operation.

CONCLUSIONS

The aortic balloon occlusion technique, as a perfusion strategy during operation, could alleviate postoperative complication. This method deserves further attention in future clinical practice for its value in treating patients with higher operative risks.

摘要

目的

全主动脉弓置换术(TAR)联合冰冻象鼻技术(FET)是治疗主动脉夹层(AD)患者的标准术式,这些患者因主动脉弓部病变而手术风险较高,需要进行长时间体外循环(CA)。我们采用主动脉球囊阻断技术,将平均 CA 时间安全地缩短至 5 分钟,并探讨其是否能改善临床终点。

方法

本回顾性观察性研究纳入了 2017 年 8 月至 2019 年 2 月期间在阜外医院接受 TAR 联合 FET 手术治疗的 AD 患者(主动脉球囊阻断组 123 例,常规方法组 221 例)。

结果

经过倾向评分匹配后,主动脉球囊阻断组和常规组的 30 天死亡率分别为 4.88%和 11.38%(P = 0.062)。多因素分析显示,主动脉球囊阻断是降低术后肾功能和肝功能损伤、缩短术后意识恢复时间和减少术中红细胞(RBC)输注的因素之一。

结论

主动脉球囊阻断技术作为一种术中灌注策略,可以减轻术后并发症。对于手术风险较高的患者,该方法值得在未来的临床实践中进一步关注。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2860/7801175/10367b871ec7/atcs-26-332-g001.jpg

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