非小细胞肺癌患者的疾病认知与生活质量：一项为期3个月的随访试点研究。
Illness Perceptions and Quality of Life in Patients with Non-Small-Cell Lung Cancer: A 3-Month Follow-Up Pilot Study.
作者信息
Vollmann Manja, Matsuda Ayako, Kroep Judith R, Kobayashi Kunihiko, Kubota Kaoru, Inoue Kenichi, Yamaoka Kazue, Putter Hein, Ramai Rajen, Nortier Johannes W R, Fischer Maarten J, Kaptein Ad A
机构信息
Socio-Medical Sciences ESHPM, Erasmus University Rotterdam, Rotterdam, the Netherlands.
Department of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan.
出版信息
Patient Relat Outcome Meas. 2020 Feb 27;11:67-71. doi: 10.2147/PROM.S238009. eCollection 2020.
PURPOSE
Examine illness perceptions, functional health and quality of life of lung cancer patients throughout chemotherapy treatment.
PATIENTS AND METHODS
Longitudinal design with baseline measure 12 days after the first chemotherapy and follow-up measure 3 months later, where illness perceptions (BIPQ), functional health, and quality of life (EORTC QLQ-C-30) were measured. A total of 21 patients with non-small-cell lung cancer took part. Non-parametric testing was performed given the pilot nature of the study and the associated relatively small sample size.
RESULTS
Small to medium changes in illness perceptions and functional health between the two measurement points were detected, with both becoming more positive. More negative illness perceptions at the beginning of the treatment were associated with less functioning and lower quality of life at both beginning and end of treatment.
CONCLUSION
Addressing illness perceptions seems a clinically relevant approach in improving functioning and quality of life of patients with non-small-cell lung cancer.
目的
研究肺癌患者在整个化疗治疗过程中的疾病认知、功能健康和生活质量。
患者与方法
采用纵向设计，在首次化疗后12天进行基线测量，3个月后进行随访测量，测量疾病认知（Brief Illness Perception Questionnaire，BIPQ）、功能健康和生活质量（欧洲癌症研究与治疗组织核心问卷，EORTC QLQ-C-30）。共有21例非小细胞肺癌患者参与。鉴于该研究的探索性本质及相关样本量相对较小，进行了非参数检验。
结果
在两个测量点之间，疾病认知和功能健康出现了小到中等程度的变化，两者都变得更加积极。治疗开始时更消极的疾病认知与治疗开始和结束时功能较差及生活质量较低相关。
结论
解决疾病认知问题似乎是改善非小细胞肺癌患者功能和生活质量的一种临床相关方法。
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