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莱姆病性心内膜炎作为一种新发传染病:文献综述

Lyme Endocarditis as an Emerging Infectious Disease: A Review of the Literature.

作者信息

Nikolić Aleksandra, Boljević Darko, Bojić Milovan, Veljković Stefan, Vuković Dragana, Paglietti Bianca, Micić Jelena, Rubino Salvatore

机构信息

Faculty of Medicine, University of Belgrade, Belgrade, Serbia.

"Dedinje" Cardiovascular Institute, Belgrade, Serbia.

出版信息

Front Microbiol. 2020 Feb 26;11:278. doi: 10.3389/fmicb.2020.00278. eCollection 2020.

Abstract

Lyme endocarditis is extremely rare manifestation of Lyme disease. The clinical manifestations of Lyme endocarditis are non-specific and can be very challenging diagnosis to make when it is the only manifestation of the disease. Until now, only a few cases where reported. Physicians should keep in mind the possibility of borrelial etiology of endocarditis in endemic areas. Appropriate valve tissue sample should be sent for histopathology, culture, and PCR especially in case of endocarditis of unknown origin PCR on heart valve samples is recommended. With more frequent PCR, spp. may be increasingly found as a cause of infective endocarditis. Prompt diagnosis and treatment of Lyme carditis may prevent surgical treatment and pacemaker implantations. Due to climate change and global warming Lyme disease is a growing problem. Rising number of Lyme disease cases we can expect and rising number of Lyme endocarditis.

摘要

莱姆病性心内膜炎是莱姆病极为罕见的一种表现形式。莱姆病性心内膜炎的临床表现不具有特异性,当它是该疾病的唯一表现时,诊断会极具挑战性。到目前为止,仅有少数病例被报道。在流行地区,医生应牢记心内膜炎由疏螺旋体病因引起的可能性。应送检合适的瓣膜组织样本进行组织病理学检查、培养及聚合酶链反应(PCR),尤其是在病因不明的心内膜炎病例中。建议对心脏瓣膜样本进行PCR检测。随着PCR检测更加频繁,疏螺旋体属可能会越来越多地被发现是感染性心内膜炎的病因。及时诊断和治疗莱姆病性心肌炎可避免手术治疗和起搏器植入。由于气候变化和全球变暖,莱姆病正成为一个日益严重的问题。我们预计莱姆病病例数量会上升,莱姆病性心内膜炎的病例数量也会上升。

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Human Tick-Borne Diseases in Australia.澳大利亚的人传蜱传疾病。
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Mitral Valve Endocarditis: A Rare Manifestation of Lyme Disease.二尖瓣心内膜炎:莱姆病的一种罕见表现。
Ann Thorac Surg. 2019 Aug;108(2):e85-e86. doi: 10.1016/j.athoracsur.2018.12.046. Epub 2019 Jan 25.
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Direct Diagnostic Tests for Lyme Disease.直接诊断莱姆病的检测方法。
Clin Infect Dis. 2019 Mar 5;68(6):1052-1057. doi: 10.1093/cid/ciy614.
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Lyme Endocarditis.莱姆心内膜炎。
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