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类风湿性关节炎患者接受全膝关节或全髋关节置换术时术前疼痛、功能及疾病活动度的种族差异:一项基于纽约的研究。

Racial disparities in pre-operative pain, function and disease activity for patients with rheumatoid arthritis undergoing Total knee or Total hip Arthroplasty: a New York based study.

作者信息

Hirsch J, Mehta B, Finik J, Navarro-Millan I, Brantner C, Mirza S, Figgie M, Parks M, Russell L, Orange D, Goodman S

机构信息

1Mount Sinai St. Luke's-West, New York, NY USA.

2Hospital for Special Surgery, 535 E 70th Street, New York, NY 10021 USA.

出版信息

BMC Rheumatol. 2020 Feb 29;4:17. doi: 10.1186/s41927-020-0117-0. eCollection 2020.

Abstract

BACKGROUND

Black and Hispanic patients with osteoarthritis have more pain and worse function than Whites at the time of arthroplasty. Whether this is true for patients with rheumatoid arthritis (RA) is unknown.

METHODS

This cross-sectional study used data on RA patients acquired between October 2013 and November 2018 prior to elective total knee (TKA) or hip arthroplasty (THA). Pain, function, and disease activity were assessed using the visual analogue scale (VAS), the Multidimensional Health Assessment Questionnaire (MDHAQ), and the Disease Activity Score (DAS28-ESR). We linked the cases to census tracts using geocoding to determine the community poverty level. Race, education, income, insurance and medications were collected via self-report. Using multivariable linear and logistic models we examined whether minority status predicted pain, function and RA disease activity at the time of arthroplasty.

RESULTS

Thirty seven (23%) of the 164 patients were Black or Hispanic (minorities). The MDHAQ and DAS28-ESR were not significantly worse while VAS pain score was significantly worse in minority patients ( = 0.03). There was no significant difference in education between the groups. Insurance varied significantly; 29% of minority patients had Medicaid vs. 0% of Whites ( < 0.0001). In the multivariable analyses minority status was not significantly associated with DAS28-ESR [ = 0.66], MDHAQ [ = 0.26], or VAS pain [ = 0.18].

CONCLUSIONS

For Black and/or Hispanic patients with RA undergoing THA or TKA at a high-volume specialty hospital, unlike Black or Hispanic patients with osteoarthritis (OA), there was no association with worse pain, function, or RA disease activity at the time of elective arthroplasty.

摘要

背景

骨关节炎患者中,黑人和西班牙裔患者在关节置换术时比白人有更多疼痛且功能更差。类风湿性关节炎(RA)患者是否如此尚不清楚。

方法

这项横断面研究使用了2013年10月至2018年11月期间择期全膝关节置换术(TKA)或髋关节置换术(THA)之前收集的RA患者数据。使用视觉模拟量表(VAS)、多维健康评估问卷(MDHAQ)和疾病活动评分(DAS28-ESR)评估疼痛、功能和疾病活动度。我们通过地理编码将病例与普查区相关联,以确定社区贫困水平。种族、教育程度、收入、保险和用药情况通过自我报告收集。我们使用多变量线性和逻辑模型来研究少数族裔身份是否能预测关节置换术时的疼痛、功能和RA疾病活动度。

结果

164例患者中有37例(23%)为黑人或西班牙裔(少数族裔)。少数族裔患者的MDHAQ和DAS28-ESR没有显著更差,但VAS疼痛评分显著更差(P = 0.03)。两组之间的教育程度没有显著差异。保险情况差异显著;29%的少数族裔患者有医疗补助,而白人患者为0%(P < 0.0001)。在多变量分析中,少数族裔身份与DAS28-ESR(P = 0.66)、MDHAQ(P = 0.26)或VAS疼痛(P = 0.18)没有显著关联。

结论

对于在一家大型专科医院接受THA或TKA的黑人和/或西班牙裔RA患者,与患有骨关节炎(OA)的黑人和/或西班牙裔患者不同,在择期关节置换术时,疼痛、功能或RA疾病活动度较差并无关联。

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