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类风湿关节炎患者行全髋关节置换术和全膝关节置换术后住院时间延长的相关因素。

Factors Associated With Increasing Length of Stay for Rheumatoid Arthritis Patients Undergoing Total Hip Arthroplasty and Total Knee Arthroplasty.

作者信息

Morse Kyle W, Heinz Nicole K, Abolade Jeremy M, Wright-Chisem Joshua, Alice Russell Linda, Zhang Meng, Mirza Serene, Pearce-Fisher Diyu, Orange Dana E, Figgie Mark P, Sculco Peter K, Goodman Susan M

机构信息

Department of Medicine, Hospital for Special Surgery, New York, NY, USA.

Department of Medicine, Weill Cornell Medicine, New York, NY, USA.

出版信息

HSS J. 2022 May;18(2):196-204. doi: 10.1177/15563316221076603. Epub 2022 Feb 22.

Abstract

Total hip arthroplasty (THA) and total knee arthroplasty (TKA) are cost-effective procedures that decrease pain and improve health-related quality of life for patients with advanced symptomatic arthritis, including rheumatoid arthritis (RA). Patients with RA have a longer length of stay (LOS) after THA or TKA than patients with osteoarthritis, yet the factors contributing to LOS have not been investigated. : We sought to identify the factors contributing to LOS for patients with RA undergoing THA and TKA at a single tertiary care orthopedic specialty hospital. : We retrospectively reviewed data from a prospectively collected cohort of 252 RA patients undergoing either THA or TKA. Demographics, RA characteristics, medications, serologies, and disease activity were collected preoperatively. Linear regression was performed to explore the relationship between LOS (log-transformed) and possible predictors. A multivariate model was constructed through backward selection using significant predictors from a univariate analysis. : Of the 252 patients with RA, 83% were women; they had a median disease duration of 14 years and moderate disease activity at the time of arthroplasty. We had LOS data on 240 (95%) of the cases. The mean LOS was 3.4 ± 1.5 days. The multivariate analysis revealed a longer LOS for RA patients who underwent TKA versus THA, were women versus men, required a blood transfusion, and took preoperative opioids. : Our retrospective study found that increased postoperative LOS in RA patients undergoing THA or TKA was associated with factors both non-modifiable (type of surgery, sex) and modifiable (postoperative blood transfusion, preoperative opioid use). These findings suggest that preoperative optimization of the patient with RA might focus on improving anemia and reducing opioid use in efforts to shorten LOS. More rigorous study is warranted.

摘要

全髋关节置换术(THA)和全膝关节置换术(TKA)是具有成本效益的手术,可减轻晚期症状性关节炎患者(包括类风湿关节炎(RA)患者)的疼痛并改善其健康相关生活质量。与骨关节炎患者相比,RA患者在接受THA或TKA后的住院时间更长,但导致住院时间延长的因素尚未得到研究。我们试图确定在一家三级护理骨科专科医院接受THA和TKA的RA患者住院时间延长的因素。我们回顾性分析了前瞻性收集的252例接受THA或TKA的RA患者的数据。术前收集了人口统计学、RA特征、药物治疗、血清学和疾病活动度等信息。进行线性回归以探讨住院时间(对数转换)与可能的预测因素之间的关系。通过向后选择,使用单变量分析中的显著预测因素构建多变量模型。在252例RA患者中,83%为女性;她们的疾病中位持续时间为14年,在关节置换术时疾病活动度为中度。我们获得了240例(95%)病例的住院时间数据。平均住院时间为3.4±1.5天。多变量分析显示,接受TKA而非THA的RA患者、女性患者、需要输血的患者以及术前使用阿片类药物的患者住院时间更长。我们的回顾性研究发现,接受THA或TKA的RA患者术后住院时间延长与不可改变的因素(手术类型、性别)和可改变因素(术后输血、术前阿片类药物使用)均有关。这些发现表明,对RA患者进行术前优化可能侧重于改善贫血和减少阿片类药物使用,以努力缩短住院时间。需要进行更严格的研究。

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