Wade Minal, Sharma Ratna, Manglani Mamta
Division of Hematology Oncology, Department of Pediatrics, Lokmanya Tilak Municipal Medical College & General Hospital, Sion, Mumbai, 400 022 India.
Indian J Hematol Blood Transfus. 2009 Jun;25(2):66-9. doi: 10.1007/s12288-009-0016-4. Epub 2009 Jul 5.
The present study was designed to study appropriateness of use of the blood components in pediatric and neonatal wards.
It was an observational study conducted in a tertiary care institute. The patients were selected from various pediatric subsections over a period of six months.
All the patients below 12 years of age, who received blood components in any of the pediatric subsections including general pediatric wards, pediatric intensive care unit, pediatric hematology section, neonatal intensive care unit and pediatric surgery ward were included in the study. Each transfusion episode was assessed to decide whether it satisfied the predetermined criteria.
Of the total 184 episodes of blood component transfusions, 153 (83.1%) episodes were appropriate and 31 (16.9%) episodes were inappropriate. Among these, fresh frozen plasma transfusions had highest inappropriate [18/41 (58%)] episodes followed by packed red cell transfusions [11/110 (35.5%)] and platelet transfusions [2/5 (6.45%)]. There was no inappropriate episode of cryoprecipitate transfusion.
The present study reinforces the importance of blood audit in the clinical setting. Judicious implementation of guidelines for use of various blood products may help decrease the inappropriate use of blood components.
本研究旨在探讨儿科和新生儿病房血液成分使用的合理性。
这是一项在三级医疗机构进行的观察性研究。在六个月的时间里,从各个儿科科室选取患者。
纳入所有12岁以下、在包括普通儿科病房、儿科重症监护病房、儿科血液科、新生儿重症监护病房和儿科外科病房在内的任何儿科科室接受血液成分治疗的患者。对每一次输血事件进行评估,以确定其是否符合预定标准。
在总共184次血液成分输血事件中,153次(83.1%)是合适的,31次(16.9%)是不合适的。其中,新鲜冰冻血浆输血的不合适事件发生率最高[18/41(58%)],其次是红细胞悬液输血[11/110(35.5%)]和血小板输血[2/5(6.45%)]。冷沉淀输血没有不合适事件。
本研究强化了临床环境中血液审核的重要性。明智地实施各种血液制品使用指南可能有助于减少血液成分的不当使用。