Mullan Clancy William, Mori Makoto, Bin Mahmood Syed Usman, Yousef Sameh, Mangi Abeel A, Elefteriades John A, Geirsson Arnar
Division of Cardiac Surgery, Department of Surgery, Yale School of Medicine, New Haven, CT, USA.
Eur J Cardiothorac Surg. 2020 Sep 1;58(3):583-589. doi: 10.1093/ejcts/ezaa067.
The effectiveness of proximal thoracic aortic aneurysm (TAA) surgery in preventing acute aortic syndromes, such as dissection and rupture, is unknown at the populational level. This study evaluated trends in acute aortic syndrome operation incidence relative to proximal aortic surgical volume in the USA.
A retrospective analysis of the National Inpatient Sample in 2005-2014 was performed. Acute aortic syndrome and TAA were identified with International Classification of Diseases, 9th edition diagnosis codes. Proximal aortic surgery was defined as the diagnosis of acute aortic syndrome or TAA with an aortic procedure and either cardioplegia, cardiopulmonary bypass or other cardiac operation. Annual rates of acute aortic syndrome surgery and proximal thoracic aneurysm surgery were adjusted for US population. Trends were evaluated using linear regression.
We identified 38 442 operations for acute aortic diagnoses and 74 953 operations for TAAs. Case volume for acute aortic syndromes increased from 0.93 to 1.63 per 100 000 (P = 0.001), and aneurysm surgery increased from 1.75 to 3.19 per 100 000 (P < 0.001). Patient and hospital characteristics differed between acute aortic and aneurysm operations, with black patients being most notably underrepresented in the aneurysm population (4.9% vs 17.0%, P < 0.001).
Acute aortic syndrome operative volume increased from 2005 to 2014 despite increasing rates of proximal aortic aneurysm surgery. Patient characteristic discrepancies were observed between the 2 groups of hospitalizations, highlighting the need for continued efforts to minimize sociodemographic disparities.
在人群层面,近端胸主动脉瘤(TAA)手术预防急性主动脉综合征(如夹层和破裂)的有效性尚不清楚。本研究评估了美国急性主动脉综合征手术发生率相对于近端主动脉手术量的趋势。
对2005 - 2014年国家住院样本进行回顾性分析。使用国际疾病分类第九版诊断代码识别急性主动脉综合征和TAA。近端主动脉手术定义为诊断为急性主动脉综合征或TAA并进行主动脉手术,且采用心脏停搏、体外循环或其他心脏手术。对美国人口调整急性主动脉综合征手术和近端胸主动脉瘤手术的年发生率。使用线性回归评估趋势。
我们确定了38442例急性主动脉诊断手术和74953例TAA手术。急性主动脉综合征的病例数从每10万人0.93例增加到1.63例(P = 0.001),动脉瘤手术从每10万人1.75例增加到3.19例(P < 0.001)。急性主动脉手术和动脉瘤手术的患者及医院特征不同,黑人患者在动脉瘤人群中的比例明显偏低(4.9%对17.0%,P < 0.001)。
尽管近端主动脉瘤手术率增加,但2005年至2014年急性主动脉综合征手术量仍有所增加。两组住院患者的特征存在差异,这突出表明需要持续努力以尽量减少社会人口统计学差异。