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老年人姑息治疗和临终关怀中的通气支持与氧疗

Ventilator Support and Oxygen Therapy in Palliative and End-of-Life Care in the Elderly.

作者信息

Scala Raffaele, Ciarleglio Giuseppina, Maccari Uberto, Granese Valentina, Salerno Laura, Madioni Chiara

机构信息

Division of Pulmonology and Respiratory Intensive Care Unit, San Donato Hospital, Arezzo, Italy.

出版信息

Turk Thorac J. 2020 Jan;21(1):54-60. doi: 10.5152/TurkThoracJ.2020.201401. Epub 2020 Jan 1.

DOI:10.5152/TurkThoracJ.2020.201401
PMID:32163365
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7020899/
Abstract

Elderly patients suffering from chronic cardio-pulmonary diseases commonly experience acute respiratory failure. As in younger patients, a well-known therapeutic approach of noninvasive mechanical ventilation is able to prevent orotracheal intubation in a large number of severe scenarios in elderly patients. In addition, this type of ventilation is frequently applied in elderly patients who refuse intubation for invasive mechanical ventilation. The rate of failure of noninvasive ventilation may be reduced by means of the integration of new technological devices (i.e., high-flow nasal cannula, extracorporeal CO removal, cough assistance and high-frequency chest wall oscillation, and fiberoptic bronchoscopy). Ethical issues with end-of-life decisions and the choice of the environment are not clearly defined in the treatment of elderly with acute respiratory insufficiency.

摘要

患有慢性心肺疾病的老年患者常出现急性呼吸衰竭。与年轻患者一样,一种广为人知的无创机械通气治疗方法能够在大量严重情况下防止老年患者进行气管插管。此外,这种通气方式常用于拒绝有创机械通气插管的老年患者。通过整合新技术设备(即高流量鼻导管、体外二氧化碳清除、咳嗽辅助和高频胸壁振荡以及纤维支气管镜检查),可降低无创通气的失败率。在老年急性呼吸功能不全的治疗中,临终决策和环境选择方面的伦理问题尚无明确界定。

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Ventilator Support and Oxygen Therapy in Palliative and End-of-Life Care in the Elderly.老年人姑息治疗和临终关怀中的通气支持与氧疗
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2
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Effect of non-invasive oxygenation strategies in immunocompromised patients with severe acute respiratory failure: a post-hoc analysis of a randomised trial.免疫功能低下的严重急性呼吸衰竭患者的无创性氧合策略的效果:一项随机试验的事后分析。
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引用本文的文献

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本文引用的文献

1
Noninvasive ventilation in acute respiratory failure: which recipe for success?急性呼吸衰竭的无创通气:成功的秘诀是什么?
Eur Respir Rev. 2018 Jul 11;27(149). doi: 10.1183/16000617.0029-2018. Print 2018 Sep 30.
2
Official ERS/ATS clinical practice guidelines: noninvasive ventilation for acute respiratory failure.ERS/ATS 官方临床实践指南:急性呼吸衰竭的无创通气。
Eur Respir J. 2017 Aug 31;50(2). doi: 10.1183/13993003.02426-2016. Print 2017 Aug.
3
Challenges on non-invasive ventilation to treat acute respiratory failure in the elderly.无创通气治疗老年人急性呼吸衰竭面临的挑战。
BMC Pulm Med. 2016 Nov 15;16(1):150. doi: 10.1186/s12890-016-0310-5.
4
Current evidence for the effectiveness of heated and humidified high flow nasal cannula supportive therapy in adult patients with respiratory failure.加热湿化高流量鼻导管支持疗法对成年呼吸衰竭患者有效性的当前证据。
Crit Care. 2016 Apr 28;20(1):109. doi: 10.1186/s13054-016-1263-z.
5
Novel Uses of Extracorporeal Membrane Oxygenation in Adults.体外膜肺氧合在成人中的新用途
Clin Chest Med. 2015 Sep;36(3):373-84. doi: 10.1016/j.ccm.2015.05.014. Epub 2015 Jun 29.
6
A preliminary randomized trial of the mechanical insufflator-exsufflator versus breath-stacking technique in patients with amyotrophic lateral sclerosis.肌萎缩侧索硬化症患者中机械吸气-呼气装置与呼吸叠加技术的初步随机试验。
Amyotroph Lateral Scler Frontotemporal Degener. 2015;16(7-8):448-55. doi: 10.3109/21678421.2015.1051992. Epub 2015 Jul 3.
7
Extracorporeal carbon dioxide removal in patients with chronic obstructive pulmonary disease: a systematic review.体外二氧化碳去除在慢性阻塞性肺疾病患者中的应用:系统评价。
Intensive Care Med. 2015 Oct;41(10):1752-62. doi: 10.1007/s00134-015-3921-z. Epub 2015 Jun 25.
8
Heated Humidified High-Flow Nasal Oxygen in Adults: Mechanisms of Action and Clinical Implications.成人经鼻高流量温热湿化氧疗:作用机制与临床意义
Chest. 2015 Jul;148(1):253-261. doi: 10.1378/chest.14-2871.
9
Integrated therapeutic strategy during noninvasive ventilation in a patient with end-stage respiratory disease.终末期呼吸系统疾病患者无创通气期间的综合治疗策略。
Respir Care. 2015 Apr;60(4):e80-5. doi: 10.4187/respcare.03303. Epub 2014 Oct 28.
10
Extracorporeal Co2 removal in hypercapnic patients at risk of noninvasive ventilation failure: a matched cohort study with historical control.高碳酸血症患者无创通气失败风险的体外二氧化碳清除:一项采用历史对照的匹配队列研究
Crit Care Med. 2015 Jan;43(1):120-7. doi: 10.1097/CCM.0000000000000607.