Department of Urology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Robotics Laboratory, Urology Department, Johns Hopkins University, Baltimore, Maryland, USA.
J Endourol. 2020 May;34(5):619-623. doi: 10.1089/end.2019.0735. Epub 2020 Apr 7.
In recent years, there has been increasing interest in the use of ultrasound guidance for endoscopic and percutaneous procedures. Kidney mockups could be used for training, however, available mockups are normally incompatible with ultrasound imaging. We developed a reproducible method to manufacture an ultrasound-compatible collecting system mockup that can be made at urology laboratories. Positive and negative molding methods were used. A three-dimensional (3D) digital model of a urinary collecting system and the overlying skin surface were segmented from computed tomography. A containment mold (negative) was made following the shape of the skin surface using 3D printing. A collecting system mold (positive) was also 3D printed, but made of a dissolvable material. The containment mold was filled with a gelatin formula with the collecting system mold submersed within. After the gelatin solidified, a solution was used to dissolve the collecting system mold, but not the gelatin, leaving a cavity with the shape of the collecting system. The gelatin was extracted from the container mockup and the collecting system cavity was filled with water. The mockup was imaged with ultrasound to assess echogenicity and suitability for simulating ultrasound-guided procedures. A clear shape corresponding to the collecting system was observed inside the gel structure. Structural integrity was maintained with no observable manufacturing marks or separation seams. Ultrasound images of the mockup demonstrated clear differentiation at the gelatin/water interface. A mock stone was placed in the collecting system and needle targeted to simulate percutaneous needle access. We developed a simple method to manufacture a personalized mockup of the renal collecting system of a patient that can be used for ultrasound-guided percutaneous needle access. Generic collecting system mockups can be used for training, and patient-specific models can be used to simulate and decide the best access path before a clinical case.
近年来,人们对在内镜和经皮操作中使用超声引导越来越感兴趣。肾脏模型可用于培训,但是,现有的模型通常与超声成像不兼容。我们开发了一种可重复的制造方法,可在泌尿科实验室制造出与超声兼容的收集系统模型。采用了正模和负模两种方法。从 CT 中对尿液收集系统和其上的皮肤表面进行三维(3D)数字模型分割。使用 3D 打印,根据皮肤表面的形状制作一个包含模具(负模)。还使用 3D 打印制作了一个收集系统模具(正模),但使用的是可溶解的材料。将包含模具充满明胶配方,将收集系统模具浸入其中。明胶凝固后,使用一种溶液溶解收集系统模具,但不会溶解明胶,从而留下一个具有收集系统形状的空腔。将明胶从容器模型中提取出来,将收集系统空腔注满水。使用超声对模型进行成像,以评估回声特性和模拟超声引导程序的适用性。在凝胶结构内部观察到与收集系统相对应的清晰形状。结构完整性得以保持,没有观察到制造痕迹或分离接缝。模型的超声图像显示在明胶/水界面上有明显的区分。在收集系统中放置一个模拟结石,用针靶向模拟经皮针穿刺。我们开发了一种简单的方法来制造患者肾脏收集系统的个性化模型,该模型可用于超声引导经皮针穿刺。通用收集系统模型可用于培训,而患者特定的模型可用于模拟和决定在临床病例之前的最佳进入路径。