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肩部假性麻痹和C反应蛋白升高是儿童脓毒性肩关节的预测因素,优于其他临床症状:一项对25例患者的回顾性病例系列研究。

Pseudo paralysis of the shoulder and increased C-reactive protein are predictive factors for septic shoulder in children superior to other clinical symptoms: a retrospective case series of 25 patients.

作者信息

Danilov Cezara, Ihle Christoph, Fernandez Francisco F, Blumenstock Gunnar, Wirth Thomas, Eberhardt Oliver

机构信息

Orthopaedic Department Olgahospital Stuttgart, Germany.

BG Trauma Center Tuebingen, Siegfried-Weller-Institute for Trauma Research, Eberhard-Karls-University, Tuebingen, Germany.

出版信息

J Child Orthop. 2020 Feb 1;14(1):85-90. doi: 10.1302/1863-2548.14.190126.

Abstract

PURPOSE

The aim of the study was to evaluate predictable parameters with the highest sensitivity used in the diagnosis of children septic shoulder arthritis.

METHODS

All children treated in our paediatric orthopaedic hospital between 2000 and 2017 with intraoperative verified septic arthritis of the shoulder were included in this retrospective study. Diagnostic procedures e.g. ultrasound, MRI, radiograph or blood samples as well as typical clinical symptoms were evaluated as predictable parameters for septic shoulder arthritis in paediatric patients. Descriptive statistics as well as sensitivity analysis were performed.

RESULTS

In all, 25 children, 20 boys and five girls, aged from eight days to 15 years, were included for further statistical analysis. All parameters included were tested for sensitivity with binomial confidence intervals (Cis) of 95%. Predictive parameters with highest sensitivity were pseudo paralysis (100%, CI 0.86 to 1.00) and C-reactive protein (CRP) (96%, CI 0.79 to 0.99) superior to temperature (52%, CI 0.3 to 0.73), white blood count (11%, CI 0.01 to 0.34), radiograph (21%, CI 0.04 to 0.50), ultrasound (71%, CI 0.47 to 0.88) or MRI (100%, CI 0.78 to 1.00).

CONCLUSION

The diagnosis of a septic arthritis of the shoulder in children can be challenging for the clinician and especially for the resident doctor. Clinical symptoms such as pseudo paralysis and increased CRP level must be considered as predictive markers not to delay further diagnostics and treatment.

LEVEL OF EVIDENCE

IV.

摘要

目的

本研究旨在评估用于诊断儿童化脓性肩关节关节炎的具有最高敏感性的可预测参数。

方法

本回顾性研究纳入了2000年至2017年间在我院儿科骨科接受手术确诊为化脓性肩关节关节炎的所有儿童。对超声、MRI、X线片或血样等诊断程序以及典型临床症状进行评估,作为儿童化脓性肩关节关节炎的可预测参数。进行了描述性统计和敏感性分析。

结果

共有25名儿童(20名男孩和5名女孩),年龄从8天至15岁,纳入进一步统计分析。对所有纳入参数进行敏感性测试,二项式置信区间(CI)为95%。敏感性最高的预测参数是假性麻痹(100%,CI 0.86至1.00)和C反应蛋白(CRP)(96%,CI 0.79至0.99),优于体温(52%,CI 0.3至0.73)、白细胞计数(11%,CI 0.01至0.34)、X线片(21%,CI 0.04至0.50)、超声(71%,CI 0.47至0.88)或MRI(100%,CI 0.78至1.00)。

结论

儿童化脓性肩关节关节炎的诊断对临床医生尤其是住院医生来说可能具有挑战性。假性麻痹和CRP水平升高等临床症状必须被视为预测指标,以免延误进一步的诊断和治疗。

证据级别

IV级。

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