Tomasello Francesco, Germanò Antonino, Lavano Angelo, Romano Alberto, Cafarella Daniele, Gorgoglione Nicola, La Torre Domenico
AOU Policlinico "G. Martino," Università degli Studi di Messina, Messina, Italy.
AOU "Mater Domini," Università degli Studi "Magna Greacia" di Catanzaro, Catanzaro, Italy.
Oper Neurosurg. 2020 Sep 1;19(3):226-233. doi: 10.1093/ons/opaa044.
Microvascular decompression (MVD) represents a milestone for the treatment of trigeminal neuralgia (TN). Nevertheless, several complications still occur and may negatively affect the outcome. We recently proposed some technical nuances for complication avoidance related to MVD.
To verify the efficacy of the proposed refinement of the standard MVD technique in terms of resolution of the pain and reduction of complication rates.
We analyzed surgical and outcome data of patients with TN using a novel surgical refinement to MVD, over the last 4 yr. Outcome variables included pain relief, facial numbness, muscular atrophy, local cutaneous occipital and temporal pain or numbness, cerebellar injury, hearing loss, cranial nerve deficits, wound infection, and cerebrospinal fluid (CSF) leak. Overall complication rate was defined as the occurrence of any of the aforementioned items.
A total of 72 consecutive patients were enrolled in the study. Pain relief was achieved in 91.6% and 88.8% of patients at 1- and 4-yr follow-up, respectively. No patient reported postoperative facial numbness during the entire follow-up period. The incidence of CSF leak was 1.4%. One patient developed a complete hearing loss and another a minor cerebellar ischemia. There was no mortality. The overall complication rate was 5.6%, but only 1.4% of patients experienced permanent sequelae.
The proposed refinement of the standard MVD technique has proved effective in maintaining excellent results in terms of pain relief while minimizing the overall complication rate associated with this surgical approach.
微血管减压术(MVD)是治疗三叉神经痛(TN)的一个里程碑。然而,仍会出现一些并发症,可能会对治疗结果产生负面影响。我们最近提出了一些与MVD相关的避免并发症的技术细节。
验证所提出的标准MVD技术改进在缓解疼痛和降低并发症发生率方面的疗效。
我们分析了过去4年中使用新型MVD手术改进方法治疗TN患者的手术和结果数据。结果变量包括疼痛缓解、面部麻木、肌肉萎缩、枕部和颞部局部皮肤疼痛或麻木、小脑损伤、听力丧失、颅神经缺损、伤口感染和脑脊液(CSF)漏。总体并发症发生率定义为上述任何一项的发生情况。
共有72例连续患者纳入本研究。在1年和4年随访时,分别有91.6%和88.8%的患者实现了疼痛缓解。在整个随访期间,没有患者报告术后面部麻木。脑脊液漏的发生率为1.4%。1例患者出现完全性听力丧失,另1例出现轻度小脑缺血。无死亡病例。总体并发症发生率为5.6%,但只有1.4%的患者出现永久性后遗症。
所提出的标准MVD技术改进已被证明在缓解疼痛方面能保持良好效果,同时将与这种手术方法相关的总体并发症发生率降至最低。