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严重退行性腰椎管狭窄症的间接减压联合外侧椎间融合术:MRI至少随访1年

Indirect decompression with lateral interbody fusion for severe degenerative lumbar spinal stenosis: minimum 1-year MRI follow-up.

作者信息

Shimizu Takayoshi, Fujibayashi Shunsuke, Otsuki Bungo, Murata Koichi, Matsuda Shuichi

出版信息

J Neurosurg Spine. 2020 Mar 13;33(1):27-34. doi: 10.3171/2020.1.SPINE191412. Print 2020 Jul 1.

Abstract

OBJECTIVE

The use of indirect decompression surgery for severe canal stenosis remains controversial. The purpose of this study was to investigate the efficacy of lateral interbody fusion (LIF) without posterior decompression in degenerative lumbar spinal spondylosis with severe stenosis on preoperative MRI.

METHODS

This is a retrospective case series from a single academic institution. The authors included 42 patients (45 surgical levels) who were preoperatively diagnosed with severe degenerative lumbar stenosis on MRI based on the previously published Schizas classification. These patients underwent LIF with supplemental pedicle screw fixation without posterior decompression. Surgical levels were limited to L3-4 and/or L4-5. All patients satisfied the minimum 1-year MRI follow-up. The authors compared the cross-sectional area (CSA) of the thecal sac and the clinical outcome scores (Japanese Orthopaedic Association [JOA] score) preoperatively, immediately postoperatively, and at the 1-year follow-up. Fusion status and disc height were evaluated based on CT scans obtained at the 1-year follow-up.

RESULTS

The CSA improved over time, increasing from 54.5 ± 19.2 mm2 preoperatively to 84.7 ± 31.8 mm2 at 3 weeks postoperatively and to 132.6 ± 37.5 mm2 at the last follow-up (average 28.3 months) (p < 0.001). The JOA score significantly improved over time (preoperatively 16.1 ± 4.1, 3 months postoperatively 24.4 ± 4.0, and 1-year follow-up 25.7 ± 2.9; p < 0.001). The fusion rate at the 1-year follow-up was 88.8%, and disc heights were significantly restored (preoperative, 6.3 mm and postoperative, 9.6 mm; p < 0.001). Patients showing poor CSA expansion (< 200% expansion rate) at the last follow-up had a higher prevalence of pseudarthrosis than patients with significant CSA expansion (> 200% expansion rate) (25.0% vs 3.4%, p < 0.001). No major perioperative complications were observed.

CONCLUSIONS

LIF with indirect decompression for degenerative lumbar disease with severe canal stenosis provided successful clinical outcomes, including restoration of disc height and indirect expansion of the thecal sac. Severe canal stenosis diagnosed on preoperative MRI itself is not a contraindication for indirect decompression surgery.

摘要

目的

对于严重椎管狭窄采用间接减压手术仍存在争议。本研究的目的是探讨在术前MRI显示为严重狭窄的退变性腰椎脊柱病中,不进行后路减压的侧方椎间融合术(LIF)的疗效。

方法

这是来自单一学术机构的回顾性病例系列研究。作者纳入了42例患者(45个手术节段),这些患者根据先前发表的Schizas分类,术前MRI诊断为严重退变性腰椎管狭窄。这些患者接受了LIF并辅以椎弓根螺钉固定,未进行后路减压。手术节段限于L3 - 4和/或L4 - 5。所有患者均满足至少1年的MRI随访。作者比较了术前、术后即刻和1年随访时的硬膜囊横截面积(CSA)以及临床结果评分(日本骨科协会[JOA]评分)。根据1年随访时获得的CT扫描评估融合状态和椎间盘高度。

结果

CSA随时间改善,术前为54.5±19.2mm²,术后3周增至84.7±31.8mm²,末次随访(平均28.3个月)时增至132.6±37.5mm²(p<0.001)。JOA评分随时间显著改善(术前16.1±4.1,术后3个月24.4±4.0,1年随访25.7±2.9;p<0.001)。1年随访时融合率为88.8%,椎间盘高度显著恢复(术前6.3mm,术后9.6mm;p<0.001)。末次随访时CSA扩张不佳(扩张率<200%)的患者假关节发生率高于CSA显著扩张(扩张率>200%)的患者(25.0%对3.4%,p<0.001)。未观察到重大围手术期并发症。

结论

对于严重椎管狭窄的退变性腰椎疾病,采用间接减压的LIF手术取得了成功的临床结果,包括椎间盘高度的恢复和硬膜囊的间接扩张。术前MRI诊断的严重椎管狭窄本身并非间接减压手术的禁忌证。

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