斜外侧椎间融合术间接减压治疗重度退行性腰椎管狭窄症:与直接减压经椎间孔/后路腰椎间融合术的对比研究。

Indirect decompression via oblique lateral interbody fusion for severe degenerative lumbar spinal stenosis: a comparative study with direct decompression transforaminal/posterior lumbar interbody fusion.

机构信息

Department of Orthopaedic Surgery, Kyoto University, Graduate School of Medicine.

Department of Orthopaedic Surgery, Kyoto University, Graduate School of Medicine.

出版信息

Spine J. 2021 Jun;21(6):963-971. doi: 10.1016/j.spinee.2021.01.025. Epub 2021 Feb 2.

Abstract

BACKGROUND CONTEXT

Previous studies have shown that oblique lateral interbody fusion (OLIF) can improve neurological symptoms via "indirect decompression." However, data are lacking in terms of its benefits when compared with conventional transforaminal lumbar interbody fusion (TLIF) and/or posterior lumbar interbody fusion (PLIF) approach, especially in patients with severe central canal stenosis.

PURPOSE

To investigate the clinical outcome of OLIF without posterior decompression versus conventional TLIF and/or PLIF in severe lumbar stenosis diagnosed on preoperative magnetic resonance imaging.

STUDY DESIGN

Retrospective comparative study.

PATIENT SAMPLE

Fifty-one patients who underwent OLIF and 41 patients who underwent conventional TLIF and/or PLIF.

OUTCOME MEASURES

Clinical outcome score by Japanese Orthopedic Association (JOA) score and radiographic outcomes (disc height and fusion rate on computed tomography scan).

MATERIALS/METHODS: We retrospectively reviewed 51 patients who underwent OLIF with supplemental percutaneous pedicle screws (55 levels; OLIF group) and 41 patients who underwent conventional TLIF and/or PLIF (47 levels; TPLIF group). The cross-sectional area of the thecal sac was measured preoperatively in OLIF and TPLIF groups, but postoperatively only in the OLIF group. All patients were diagnosed with severe stenosis based on Schizas classification (Grade C or D) on magnetic resonance imaging. We compared radiographic and clinical outcome scores (JOA score) between the 2 groups at 1 year of follow-up. The radiographic evaluation included the fusion status and disc height on computed tomography scan. Surgical data and perioperative complications were also investigated.

RESULTS

The baseline demographic data of the 2 groups were equivalent in preoperative diagnosis, JOA score, and disc height and/or angle. The cross-sectional area significantly increased postoperatively, which confirmed indirect decompressive effect in the OLIF group. The JOA score improved in both groups at the 1-year follow up (76.6% vs. 73.5% improvement rate in the OLIF and TPLIF groups, respectively). The fusion rate at the 1-year follow-up was higher in the OLIF group than in the TPLIF group (87.2% vs. 57.4%). The disc height restoration was also better in the OLIF group. The operative data demonstrated less estimated blood loss and operative time in the OLIF group.

CONCLUSIONS

OLIF and conventional TLIF and/or PLIF demonstrated comparable short-term clinical outcomes in the treatment of severe degenerative lumbar stenosis. However, the surgical and radiographic outcomes were better in the OLIF group. Surgeons should choose an appropriate approach on a case by case basis, recognizing the perioperative complications specific to each fusion procedure.

摘要

背景

先前的研究表明,斜外侧腰椎间融合术(OLIF)可通过“间接减压”改善神经症状。然而,与传统的经椎间孔腰椎间融合术(TLIF)和/或后路腰椎间融合术(PLIF)相比,OLIF 对严重中央管狭窄的患者的益处的数据尚缺乏。

目的

研究术前磁共振成像诊断为严重腰椎管狭窄的患者,OLIF 不进行后路减压与传统 TLIF 和/或 PLIF 的临床结果。

研究设计

回顾性对比研究。

患者样本

51 例行 OLIF 患者和 41 例行传统 TLIF 和/或 PLIF 患者。

研究结果

采用日本矫形协会(JOA)评分评估临床疗效,采用 CT 扫描评估影像学结果(椎间盘高度和融合率)。

材料/方法:我们回顾性分析了 51 例行 OLIF 并附加经皮椎弓根螺钉(55 个节段;OLIF 组)和 41 例行传统 TLIF 和/或 PLIF(47 个节段;TLIF 组)的患者。OLIF 和 TLIF 组患者在术前测量硬脊膜囊的横截面积,但仅在 OLIF 组患者术后测量。所有患者均根据磁共振成像的 Schizas 分级(C 或 D 级)诊断为严重狭窄。我们比较了两组患者在 1 年随访时的影像学和临床疗效评分(JOA 评分)。影像学评估包括 CT 扫描的融合状态和椎间盘高度。还研究了手术数据和围手术期并发症。

结果

两组患者的术前诊断、JOA 评分、椎间盘高度和/或角度的基线人口统计学数据相当。OLIF 组术后横截面积显著增加,证实了间接减压效果。两组患者在 1 年随访时 JOA 评分均有所改善(OLIF 组和 TLIF 组的改善率分别为 76.6%和 73.5%)。OLIF 组的融合率高于 TLIF 组(OLIF 组 87.2%,TLIF 组 57.4%)。OLIF 组的椎间盘高度恢复也更好。OLIF 组的手术数据显示失血量和手术时间更少。

结论

OLIF 和传统 TLIF 和/或 PLIF 治疗严重退行性腰椎管狭窄症的短期临床疗效相当。然而,OLIF 组的手术和影像学结果更好。外科医生应根据具体情况选择合适的方法,并认识到每种融合术的围手术期并发症。

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