常见变异免疫缺陷病中滤泡性CD8 T细胞的耗竭表型 - Suppr | 超能文献

文献检索
文档翻译
深度研究
学术资讯

Zotero 插件

邀请有礼
套餐&价格
历史记录

应用&插件

Zotero 插件浏览器插件 Mac 客户端 Windows 客户端微信小程序

定价

高级版会员购买积分包购买API积分包

服务

文献检索文档翻译深度研究 API 文档 MCP 服务

关于我们

关于 Suppr 公司介绍联系我们用户协议隐私条款

关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究

粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

常见变异免疫缺陷病中滤泡性CD8 T细胞的耗竭表型 - Suppr | 超能文献

Exhausted phenotype of follicular CD8 T cells in CVID.

作者信息

Klocperk Adam, Unger Susanne, Friedmann David, Seidl Maximilian, Zoldan Katharina, Pfeiffer Jens, Hausmann Oliver, Benes Vladimir, Andrieux Geoffroy, Boettler Tobias, Sediva Anna, Bengsch Bertram, Warnatz Klaus

机构信息

Divison of Immunodeficiency, Department of Rheumatology and Clinical Immunology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany; Center for Chronic Immunodeficiency (CCI), Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany; Department of Immunology, 2nd Faculty of Medicine, Charles University in Prague and University Hospital in Motol, Prague, Czech Republic.

Divison of Immunodeficiency, Department of Rheumatology and Clinical Immunology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany; Center for Chronic Immunodeficiency (CCI), Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany; Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland.

出版信息

J Allergy Clin Immunol. 2020 Oct;146(4):912-915.e13. doi: 10.1016/j.jaci.2020.02.025. Epub 2020 Mar 10.

DOI:10.1016/j.jaci.2020.02.025

Abstract

摘要

相似文献

1

Exhausted phenotype of follicular CD8 T cells in CVID.常见变异免疫缺陷病中滤泡性CD8 T细胞的耗竭表型

J Allergy Clin Immunol. 2020 Oct;146(4):912-915.e13. doi: 10.1016/j.jaci.2020.02.025. Epub 2020 Mar 10.

2

Analysis of bulk and virus-specific CD8+ T cells reveals advanced differentiation of CD8+ T cells in patients with common variable immunodeficiency.对 bulk 和病毒特异性 CD8+T 细胞的分析显示，普通变异性免疫缺陷患者的 CD8+T 细胞分化程度较高。

Clin Immunol. 2011 Nov;141(2):177-86. doi: 10.1016/j.clim.2011.07.006. Epub 2011 Aug 5.

3

Investigation of common variable immunodeficiency patients and healthy individuals using autoimmune lymphoproliferative syndrome biomarkers.自身免疫性淋巴组织增生综合征标志物在普通可变免疫缺陷患者与健康个体中的应用研究。

Hum Immunol. 2013 Dec;74(12):1531-5. doi: 10.1016/j.humimm.2013.08.266. Epub 2013 Aug 28.

4

Immunophenotypic profile of T cells in common variable immunodeficiency: is there an association with different clinical findings?常见可变免疫缺陷中T细胞的免疫表型特征：与不同临床发现是否存在关联？

Allergol Immunopathol (Madr). 2009 Jan-Feb;37(1):14-20. doi: 10.1016/s0301-0546(09)70246-0.

5

Mutation in IRF2BP2 is responsible for a familial form of common variable immunodeficiency disorder.IRF2BP2基因的突变是常见可变免疫缺陷障碍的一种家族性形式的病因。

J Allergy Clin Immunol. 2016 Aug;138(2):544-550.e4. doi: 10.1016/j.jaci.2016.01.018. Epub 2016 Mar 23.

6

Current Understanding and Recent Developments in Common Variable Immunodeficiency Associated Autoimmunity.常见可变免疫缺陷相关自身免疫的当前认识和最新进展。

Front Immunol. 2019 Dec 10;10:2753. doi: 10.3389/fimmu.2019.02753. eCollection 2019.

7

Analyzing the Effect of Aging on CD8+ T-Cell Phenotype Using Flow Cytometry.使用流式细胞术分析衰老对CD8 + T细胞表型的影响。

Methods Mol Biol. 2015;1343:115-9. doi: 10.1007/978-1-4939-2963-4_10.

8

Monozygotic Twins Concordant for Common Variable Immunodeficiency: Strikingly Similar Clinical and Immune Profile Associated With a Polygenic Burden.同卵双胞胎共患普通可变免疫缺陷：与多基因负担相关的惊人相似临床和免疫特征。

Front Immunol. 2019 Nov 22;10:2503. doi: 10.3389/fimmu.2019.02503. eCollection 2019.

9

Elevated levels of activated CD4 T cells in common variable immunodeficiency: association with clinical findings.普通可变免疫缺陷中活化CD4 T细胞水平升高：与临床发现的关联。

Allergol Immunopathol (Madr). 2006 Jul-Aug;34(4):131-5. doi: 10.1157/13091037.

10

The T cell response to persistent herpes virus infections in common variable immunodeficiency.常见变异型免疫缺陷中T细胞对持续性疱疹病毒感染的反应。

Clin Exp Immunol. 2006 Nov;146(2):234-42. doi: 10.1111/j.1365-2249.2006.03209.x.

引用本文的文献

1

Influence of Splenomegaly and Splenectomy on the Immune Cell Profile of Patients with Common Variable Immunodeficiency Disease.脾肿大和脾切除对普通变异性免疫缺陷病患者免疫细胞谱的影响。

J Clin Immunol. 2024 Jan 17;44(2):46. doi: 10.1007/s10875-023-01648-8.

2

Immune checkpoint status and exhaustion-related phenotypes of CD8 T cells from the tumor-draining regional lymph nodes in breast cancer.乳腺癌肿瘤引流区域淋巴结中 CD8 T 细胞的免疫检查点状态和衰竭相关表型。

Cancer Med. 2023 Dec;12(24):22196-22205. doi: 10.1002/cam4.6802. Epub 2023 Dec 8.

3

Lymphoid stromal cells - potential implications for the pathogenesis of CVID.

淋巴间质细胞 - 对 CVID 发病机制的潜在影响。

Front Immunol. 2023 Feb 17;14:1122905. doi: 10.3389/fimmu.2023.1122905. eCollection 2023.

4

Raised Serum Markers of T Cell Activation and Exhaustion in Granulomatous-Lymphocytic Interstitial Lung Disease in Common Variable Immunodeficiency.常见可变免疫缺陷中的肉芽肿性淋巴细胞性间质性肺病中 T 细胞激活和耗竭的血清标志物升高。

J Clin Immunol. 2022 Oct;42(7):1553-1563. doi: 10.1007/s10875-022-01318-1. Epub 2022 Jul 5.

5

Distinct CD8 T Cell Populations with Differential Exhaustion Profiles Associate with Secondary Complications in Common Variable Immunodeficiency.不同耗尽特征的 CD8 T 细胞群体与常见可变免疫缺陷的继发并发症相关。

J Clin Immunol. 2022 Aug;42(6):1254-1269. doi: 10.1007/s10875-022-01291-9. Epub 2022 May 19.

6

Follicular helper T cell signature of replicative exhaustion, apoptosis, and senescence in common variable immunodeficiency.常见可变免疫缺陷中复制性耗竭、细胞凋亡和衰老滤泡辅助 T 细胞的特征。

Eur J Immunol. 2022 Jul;52(7):1171-1189. doi: 10.1002/eji.202149480. Epub 2022 May 29.

7

B cells promote CD8 T cell primary and memory responses to subunit vaccines.B 细胞促进亚单位疫苗诱导的 CD8 T 细胞初次和记忆应答。

Cell Rep. 2021 Aug 24;36(8):109591. doi: 10.1016/j.celrep.2021.109591.

8

Immune Monitoring of Patients With Primary Immune Regulation Disorders Unravels Higher Frequencies of Follicular T Cells With Different Profiles That Associate With Alterations in B Cell Subsets.原发性免疫调节紊乱患者的免疫监测揭示了具有不同特征的滤泡性 T 细胞的更高频率，这些细胞与 B 细胞亚群的改变相关。

Front Immunol. 2020 Oct 29;11:576724. doi: 10.3389/fimmu.2020.576724. eCollection 2020.

9

From infections to autoimmunity: Diagnostic challenges in common variable immunodeficiency.从感染到自身免疫：常见可变免疫缺陷的诊断挑战

World J Clin Cases. 2020 Sep 26;8(18):3942-3955. doi: 10.12998/wjcc.v8.i18.3942.

10

High Numbers and Densities of PD1 T-Follicular Helper Cells in Triple-Negative Breast Cancer Draining Lymph Nodes Are Associated with Lower Survival.三阴性乳腺癌引流淋巴结中 PD1+T 滤泡辅助细胞数量和密度较高与生存率降低相关。

Int J Mol Sci. 2020 Aug 19;21(17):5948. doi: 10.3390/ijms21175948.