Pawar Richa, Brar Komal, Malhotra Chanchal, Chhabra Sonia, Rana Deepshikha, Gupta Anubha
Department of Pathology, Pt. B D Sharma PGIMS, Rohtak, India.
Department of Oncosurgery, Bhagwan Mahavir Cancer Hospital, Jaipur, India.
Int J Surg Case Rep. 2020;68:170-173. doi: 10.1016/j.ijscr.2020.02.029. Epub 2020 Feb 19.
Respiratory distress is an uncommon clinical event after caesarean section and occurs due to pulmonary thromboembolism. Various causes of pulmonary thromboembolism are thrombophlebitis, ovarian venous thrombosis and mesenteric vein thrombosis.
We report a case of 30 year old female who presented with respiratory distress after eight days of uneventful caesarian section. On emergency explorative laparotomy, small gut was found to be gangrenous, so resection of the segment was performed. On histopathological examination, there was ischaemic necrosis of bowel with presence of large thrombus in mesenteric vessel. On correlating radiological findings of pulmonary thromboembolism and mesenteric vessel thrombosis with bad obstetric history, a possibility of Antiphospholipid syndrome (APS) was suggested in this case. Unfortunately, patient died the day following laparotomy so there was insufficient time to evaluate the patient for thrombophilic disorders.
Pregnancy and perpeurium are associated with higher risk of thrombosis as these are hypercoagulable states. Operative delivery and history of thrombophilia in previous pregnancies (APS) are other predisposing factors which lead to increased thrombotic state and pulmonary thromboembolism.
High index of suspicion for thrombophilic disorders is required in postpartum patients presenting with respiratory distress as prompt diagnosis and urgent intervention can save patient's life.
呼吸窘迫是剖宫产术后罕见的临床事件,由肺血栓栓塞引起。肺血栓栓塞的各种病因包括血栓性静脉炎、卵巢静脉血栓形成和肠系膜静脉血栓形成。
我们报告一例30岁女性,在剖宫产术后八天无异常情况下出现呼吸窘迫。在急诊剖腹探查术中,发现小肠坏疽,因此进行了该段小肠切除术。组织病理学检查显示肠缺血坏死,肠系膜血管内有大血栓。将肺血栓栓塞和肠系膜血管血栓形成的影像学检查结果与不良产科病史相关联后,该病例提示可能患有抗磷脂综合征(APS)。不幸的是,患者在剖腹术后第二天死亡,因此没有足够时间对患者进行血栓形成倾向疾病的评估。
妊娠和产褥期与血栓形成风险较高相关,因为这些时期处于高凝状态。手术分娩和既往妊娠的血栓形成倾向病史(APS)是导致血栓形成状态增加和肺血栓栓塞的其他易感因素。
对于出现呼吸窘迫的产后患者,需要高度怀疑血栓形成倾向疾病,因为及时诊断和紧急干预可以挽救患者生命。