Multiple sclerosis: diagnostic value of computerized tomography with delayed scanning after a double-dose of contrast medium in comparison with other diagnostic tests.

In 63 cases of clinical definite or suspected MS we compared the results of CSF analysis, VEP, BAEP, CT scanning without and after double dose contrast, in 17 cases also those of MRT. We found that CSF analysis had the highest rate of abnormal findings, followed by MRT. VEP and CT with double dose contrast showed similar sensitivity, while BAEP and CT without contrast had disappointing results. We think that CT with delayed scanning after double dose contrast can be a very useful investigation in early and doubtful cases of MS, until MRT will become a more widespread and less expensive investigation.