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疾病、药物还是食物?组织学中的食物样本可能会与胃肠道中的药物和寄生虫相混淆。

Disease, drugs, or dinner? Food histology can mimic drugs and parasites in the gastrointestinal tract.

机构信息

Department of Pathology, New York Medical College, Westchester Medical Center, Valhalla, NY, USA.

Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA, USA.

出版信息

Virchows Arch. 2020 Oct;477(4):593-595. doi: 10.1007/s00428-020-02793-w. Epub 2020 Mar 13.

DOI:10.1007/s00428-020-02793-w
PMID:32170449
Abstract

Microscopic foreign objects are sometimes found in gastrointestinal (GI) tract specimens. Some signify important diagnostic findings, such as parasitic or bacterial organisms and some medication resins. Partially digested fruits and vegetables can also be present, and some have been described in the literature as potential mimickers of clinically important findings. While animal protein appears as skeletal muscle on histologic examination, fruits and vegetables can show a wide variation under the microscope. To our knowledge, a thorough histologic examination of commonly eaten fruits and vegetables has not been published in the pathology literature. Herein, we present key morphologic features of fruits and vegetables that might be found in GI specimens, emphasizing potential mimics of significant pathologic findings.

摘要

在胃肠道(GI)标本中有时会发现微小的异物。有些异物具有重要的诊断意义,例如寄生虫或细菌生物体以及某些药物树脂。部分消化的水果和蔬菜也可能存在,并且有些已在文献中被描述为临床重要发现的潜在模拟物。虽然在组织学检查中动物蛋白表现为骨骼肌,但在显微镜下,水果和蔬菜可能会有很大的差异。据我们所知,病理学文献中尚未发表过对常见食用水果和蔬菜进行的彻底组织学检查。在此,我们介绍了可能在 GI 标本中发现的水果和蔬菜的关键形态特征,重点强调了重要病理发现的潜在模拟物。

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