Narayan M, Limbachiya S, Balasubramanian D, Subramaniam N, Thankappan K, Iyer S
Department of Head and Neck Oncology, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Coimbatore, India.
J Laryngol Otol. 2020 Apr;134(4):350-353. doi: 10.1017/S0022215120000596. Epub 2020 Mar 16.
Pharyngocutaneous fistulae are dreaded complications following total laryngectomy. This paper presents our experience using 3-5 ml gastrografin to detect pharyngeal leaks following total laryngectomy, and compares post-operative videofluoroscopy with clinical follow-up findings in the detection of pharyngocutaneous fistulae.
A retrospective case-control study was conducted of total laryngectomy patients. The control group (n = 85) was assessed clinically for development of pharyngocutaneous fistulae, while the study group (n = 52) underwent small-volume (3-5 ml) post-operative gastrografin videofluoroscopy.
In the control group, 24 of 85 patients (28 per cent) developed pharyngocutaneous fistulae, with 6 requiring surgical correction. In the study group, 24 of 52 patients (46 per cent) had videofluoroscopy-detected pharyngeal leaks; 4 patients (8 per cent) developed pharyngocutaneous fistulae, but all cases resolved following non-surgical management. Patients who underwent videofluoroscopy had a significantly lower risk of developing pharyngocutaneous fistulae; sensitivity and specificity in the detection of pharyngocutaneous fistulae were 58 per cent and 100 per cent respectively.
Small-volume gastrografin videofluoroscopy reliably identified small pharyngeal leaks. Routine use in total laryngectomy combined with withholding feeds in cases of early leaks may prevent the development of pharyngocutaneous fistulae.
咽皮肤瘘是全喉切除术后令人担忧的并发症。本文介绍了我们使用3 - 5毫升泛影葡胺检测全喉切除术后咽瘘的经验,并比较了术后视频透视检查与临床随访结果在检测咽皮肤瘘方面的差异。
对全喉切除患者进行了一项回顾性病例对照研究。对照组(n = 85)通过临床评估咽皮肤瘘的发生情况,而研究组(n = 52)在术后接受了小剂量(3 - 5毫升)泛影葡胺视频透视检查。
在对照组中,85例患者中有24例(28%)发生了咽皮肤瘘,其中6例需要手术矫正。在研究组中,52例患者中有24例(46%)通过视频透视检查发现有咽瘘;4例患者(8%)发生了咽皮肤瘘,但所有病例经非手术治疗后均痊愈。接受视频透视检查的患者发生咽皮肤瘘的风险显著较低;检测咽皮肤瘘的敏感性和特异性分别为58%和100%。
小剂量泛影葡胺视频透视检查能可靠地识别小的咽瘘。在全喉切除术中常规使用,并在早期瘘的情况下停止喂食,可能会预防咽皮肤瘘的发生。