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小儿体外膜肺氧合:单血管插管的经验

Pediatric extracorporeal membrane oxygenation: Our experience with single-vessel cannulation.

作者信息

Duyu Muhterem, Sefer Asena Pınar

机构信息

Department of Pediatrics, Pediatric Intensive Care Unit, Medeniyet University Göztepe Training and Research Hospital, Istanbul, Turkey.

Department of Pediatrics, Medeniyet University Göztepe Training and Research Hospital, Istanbul, Turkey.

出版信息

Turk Gogus Kalp Damar Cerrahisi Derg. 2020 Jan 23;28(1):92-100. doi: 10.5606/tgkdc.dergisi.2020.18359. eCollection 2020 Jan.

DOI:10.5606/tgkdc.dergisi.2020.18359
PMID:32175148
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7067028/
Abstract

BACKGROUND

In this study, we present our experience with bicaval, dual-lumen, venovenous extracorporeal membrane oxygenation in pediatric patients with severe respiratory failure.

METHODS

Between September 2015 and May 2019, a total of nine pediatric patients (7 males, 2 females; median age 3.1 years; range, 0.3 to 7.4 years) hospitalized in the pediatric intensive care unit due to severe respiratory failure who were cannulated using a bicaval, dual-lumen, venovenous catheter were retrospectively analyzed. Patient demographics, cannulation details, complication of catheter use, and outcomes were recorded.

RESULTS

The median duration of extracorporeal membrane oxygenation support was nine (range, 2 to 32) days. One patient required conversion to venoarterial extracorporeal membrane oxygenation and one patient required conversion to conventional double-cannulated venovenous extracorporeal membrane oxygenation. Of the patients, 33% suffered from bleeding complications. There were no cannula- or circuit-related complications. Adequate oxygenation and flow were obtained in all patients, except one. No mortalities were directly associated with the cannulation strategy used.

CONCLUSION

The bicaval, dual-lumen cannula can be safely used in pediatric patients with minimal complication rates and is our preferred method for venovenous extracorporeal membrane oxygenation support.

摘要

背景

在本研究中,我们介绍了双腔、双腔静脉 - 静脉体外膜肺氧合在小儿严重呼吸衰竭患者中的应用经验。

方法

回顾性分析2015年9月至2019年5月期间,9例因严重呼吸衰竭入住儿科重症监护病房的患儿(7例男性,2例女性;中位年龄3.1岁;范围0.3至7.4岁),这些患儿使用双腔、双腔静脉导管进行插管。记录患者的人口统计学资料、插管细节、导管使用并发症及结局。

结果

体外膜肺氧合支持的中位持续时间为9天(范围2至32天)。1例患者需要转换为静脉 - 动脉体外膜肺氧合,1例患者需要转换为传统的双腔静脉 - 静脉体外膜肺氧合。33%的患者出现出血并发症。未发生与插管或回路相关的并发症。除1例患者外,所有患者均获得了足够的氧合和血流量。没有死亡与所采用的插管策略直接相关。

结论

双腔、双腔静脉插管可安全用于小儿患者,并发症发生率极低,是我们进行静脉 - 静脉体外膜肺氧合支持的首选方法。

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本文引用的文献

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Intensivists Performed Percutaneous Bicaval Double-Lumen Echo-Guided Extracorporeal Membrane Oxygenation Cannulation at Bedside in Newborns and Children: A Retrospective Analysis.床旁经皮腔静脉双腔超声引导体外膜肺氧合插管在新生儿和儿童中的应用:回顾性分析。
Pediatr Crit Care Med. 2019 Jun;20(6):551-559. doi: 10.1097/PCC.0000000000001918.
2
Vascular anatomical considerations and clinical decision making during insertion of the Avalon Elite Dual Lumen single-site veno-venous ECMO cannula in children weighing less than 20 kg.体重小于20kg儿童插入Avalon Elite双腔单部位静脉-静脉体外膜肺氧合插管时的血管解剖学考量及临床决策
Perfusion. 2019 May;34(4):267-271. doi: 10.1177/0267659118815104. Epub 2018 Dec 11.
3
Comparing Percutaneous to Open Access for Extracorporeal Membrane Oxygenation in Pediatric Respiratory Failure.比较经皮与开放入路在小儿呼吸衰竭体外膜肺氧合中的应用。
Pediatr Crit Care Med. 2018 Oct;19(10):981-991. doi: 10.1097/PCC.0000000000001691.
4
Extracorporeal Life Support Organization Registry International Report 2016.体外生命支持组织2016年国际注册报告
ASAIO J. 2017 Jan/Feb;63(1):60-67. doi: 10.1097/MAT.0000000000000475.
5
Initial experience with single-vessel cannulation for venovenous extracorporeal membrane oxygenation in pediatric respiratory failure.小儿呼吸衰竭行单静脉插管建立体外膜肺氧合的初步经验。
Pediatr Crit Care Med. 2013 May;14(4):366-73. doi: 10.1097/PCC.0b013e31828a70dc.
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Right ventricular rupture and tamponade caused by malposition of the Avalon cannula for venovenous extracorporeal membrane oxygenation.用于静脉-静脉体外膜肺氧合的阿瓦隆插管位置不当导致右心室破裂和心包填塞。
J Cardiothorac Surg. 2012 Apr 20;7:36. doi: 10.1186/1749-8090-7-36.
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