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一例被遗忘的甲状腺病例:慢性未经治疗的甲状腺功能减退症的后遗症

A Case of the Forgotten Thyroid: The Sequelae of Chronic Untreated Hypothyroidism.

作者信息

Weinstein Melanie, Pasarica Magdalena

机构信息

Medical Education and Simulation, University of Central Florida College of Medicine, Orlando, USA.

Family Medicine, University of Central Florida College of Medicine, Orlando, USA.

出版信息

Cureus. 2019 Mar 12;11(3):e4240. doi: 10.7759/cureus.4240.

DOI:10.7759/cureus.4240
PMID:32175200
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7053559/
Abstract

Hypothyroidism is a common endocrine disorder frequently caused by iodine deficiency, autoimmune disease, or as a result of certain medical treatments such as radioactive iodine. We report a 57-year-old woman 21 years pos-radioiodine ablation therapy for Graves' disease. She presented to the clinic after more than two decades without medical care with a variety of symptoms, including a left-sided lower facial droop and gait instability, and was found to have bradycardia, hyperlipidemia, and mild depression. After evaluation for vitamin deficiencies, anemia, thyroid dysfunction, and stroke, her symptoms were attributed to iatrogenic hypothyroidism. She was started on appropriate thyroid replacement therapy with subsequent symptom resolution. Patients receiving thyroid destructive therapy require education and close follow-up to prevent the development of severe hypothyroidism and its associated sequelae, which can be easily improved with simple, cost-effective thyroid replacement therapy.

摘要

甲状腺功能减退是一种常见的内分泌疾病,通常由碘缺乏、自身免疫性疾病或某些医学治疗(如放射性碘治疗)引起。我们报告了一名57岁女性,她在接受放射性碘消融治疗格雷夫斯病21年后前来就诊。她在二十多年未接受医疗护理后到诊所就诊,出现了多种症状,包括左侧下面部下垂和步态不稳,检查发现有心动过缓、高脂血症和轻度抑郁。在对维生素缺乏、贫血、甲状腺功能障碍和中风进行评估后,她的症状被归因于医源性甲状腺功能减退。她开始接受适当的甲状腺替代治疗,随后症状得到缓解。接受甲状腺破坏治疗的患者需要接受教育并密切随访,以预防严重甲状腺功能减退及其相关后遗症的发生,而简单且经济有效的甲状腺替代治疗可以很容易地改善这些情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24d8/7053559/6e15ae47ae0c/cureus-0011-00000004240-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24d8/7053559/02c68dc7146f/cureus-0011-00000004240-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24d8/7053559/19057732bcfb/cureus-0011-00000004240-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24d8/7053559/6e15ae47ae0c/cureus-0011-00000004240-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24d8/7053559/02c68dc7146f/cureus-0011-00000004240-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24d8/7053559/19057732bcfb/cureus-0011-00000004240-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24d8/7053559/6e15ae47ae0c/cureus-0011-00000004240-i03.jpg

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本文引用的文献

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