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RNA-seq Analysis of Wild-Type vs. FOXC2-Deficient Melanoma Cells Reveals a Role for the FOXC2 Transcription Factor in the Regulation of Multiple Oncogenic Pathways.

作者信息

Hargadon Kristian M, Williams Corey J

机构信息

Hargadon Laboratory, Department of Biology, Hampden-Sydney College, Hampden-Sydney, VA, United States.

出版信息

Front Oncol. 2020 Feb 27;10:267. doi: 10.3389/fonc.2020.00267. eCollection 2020.

DOI:10.3389/fonc.2020.00267
PMID:32175283
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7056877/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b56d/7056877/369946d868fb/fonc-10-00267-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b56d/7056877/369946d868fb/fonc-10-00267-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b56d/7056877/369946d868fb/fonc-10-00267-g0001.jpg

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本文引用的文献

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2
The Epithelial to Mesenchymal Transition Promotes Glutamine Independence by Suppressing Expression.上皮-间质转化通过抑制[某种物质]表达促进谷氨酰胺非依赖性。 （注：原文中“Suppressing Expression”这里应该缺失了具体抑制表达的物质，我按字面翻译并补充了[某种物质]）
Cancers (Basel). 2019 Oct 22;11(10):1610. doi: 10.3390/cancers11101610.
3
RIG-I activation is critical for responsiveness to checkpoint blockade.
RIG-I 激活对于响应检查点阻断至关重要。
Sci Immunol. 2019 Sep 13;4(39). doi: 10.1126/sciimmunol.aau8943.
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FOXC2 expression and epithelial-mesenchymal phenotypes are associated with castration resistance, metastasis and survival in prostate cancer.FOXC2 的表达与上皮间质表型与前列腺癌的去势抵抗、转移和生存相关。
J Pathol Clin Res. 2019 Oct;5(4):272-286. doi: 10.1002/cjp2.142. Epub 2019 Oct 1.
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Induction of tolerogenic dendritic cells by activated TGF-β/Akt/Smad2 signaling in RIG-I-deficient stemness-high human liver cancer cells.RIG-I 缺陷型干性高的人肝癌细胞中激活的 TGF-β/Akt/Smad2 信号诱导免疫耐受树突状细胞。
BMC Cancer. 2019 May 14;19(1):439. doi: 10.1186/s12885-019-5670-9.
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