Sinistrero G, Sismondi P, Zola P
Servizio di Radioterapia, Clinica Pinna Pintor, Torino, Italy.
Radiother Oncol. 1988 Dec;13(4):257-65. doi: 10.1016/0167-8140(88)90221-6.
The results of treatment of uterine cervix cancer by radiotherapy alone in 259 patients in the period January 1973 to December 1984 are reported. They are analyzed according to patients age, stage, tumor volume, extent of parametrial infiltration, hydronephrosis and nodal status. It is shown that age, tumor volume, extent of parametrial invasion and nodal metastases are the main prognostic factors. Analysis of pelvic failures shows that external radiotherapy followed by curietherapy seems to be the best method for patients with T2b and T3b tumors of small volume (less than 60 mm in diameter), particularly when parametrial infiltration is limited. Patients with T2b tumors of large volume (barrel shaped) seem to need a more aggressive approach, and a higher number of complications are therefore expected. Patients with T3b and massive parametrial infiltration, with T4 and nodal metastases need new and different approaches, possibly including adjuvant chemotherapy.
报告了1973年1月至1984年12月期间259例仅接受放射治疗的子宫颈癌患者的治疗结果。根据患者年龄、分期、肿瘤体积、宫旁浸润程度、肾积水和淋巴结状态进行分析。结果表明,年龄、肿瘤体积、宫旁浸润程度和淋巴结转移是主要的预后因素。盆腔复发分析显示,对于小体积(直径小于60mm)的T2b和T3b肿瘤患者,外照射后加腔内放疗似乎是最佳方法,尤其是当宫旁浸润有限时。大体积(桶状)T2b肿瘤患者似乎需要更积极的治疗方法,因此预计会有更多并发症。T3b和广泛宫旁浸润、T4和有淋巴结转移的患者需要新的不同治疗方法,可能包括辅助化疗。