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[法国一个中等规模城镇的脑血管意外发病率]

[Incidence of cerebrovascular accidents in a medium-sized French town].

作者信息

Giroud M, Beuriat P, Vion P, Gisselmann A, D'Athis P, Dusserre L, Dumas R

机构信息

Registre Dijonnais des Accidents Vasculaires Cérébraux Service de Neurologie, Hôpital Géneéral, Dijon.

出版信息

Rev Epidemiol Sante Publique. 1988;36(4-5):360-8.

PMID:3217575
Abstract

Beginning in 1985, the Dijon Stroke Registry has identified every case of stroke occurring in this city of 140,000 inhabitants. The systematic use of a CT scan and multiple other sources of information ranging from hospital doctors to general practitioners make it possible for us to have virtually exhaustive data on stroke incidence. The gross incidence was 170 per 100,000 among men and 126 per 100,000 among women. Specific incidence by age and sex shows female predominance up to 30 years of age, and male predominance among victims from 30 to 80 years old. Beyond 80, rates were identical for both sexes. In 68% of the cases, the strokes were caused by infarct; in 12%, by lacunae; in 15%, by cerebral hemorrhage; in 5%, by subarachnoid hemorrhage. Significant differences existed in this distribution according to age, with a clear predominance of young people among those having subarachnoid hemorrhage, while, for those over 40, cerebral hemorrhages were frequent; the proportion of infarct increased with age for both sexes. A peak of incidence for infarct appeared during winter, while transient ischemic accident was more frequent in summer. Cerebral hemorrhage had a similar incidence throughout the year. Mortality was high during the first month (12.5% during the first week, 21.5% during the first month), and reached 30% during the first year. These results are comparable to those generally observed among white occidental populations. They confirm the limited incidence of hemorrhages (contrary to what has been observed in Japan), emphasize the important and often underestimated role of lacunar syndromes, and the seasonal variations specific to each mechanism.

摘要

自1985年起,第戎卒中登记处已识别出这座拥有14万居民的城市中发生的每一例卒中病例。通过系统使用CT扫描以及从医院医生到全科医生等多种其他信息来源,我们得以获取几乎详尽的卒中发病率数据。男性的总发病率为每10万人170例,女性为每10万人126例。按年龄和性别划分的特定发病率显示,30岁以下女性占主导,30至80岁的受害者中男性占主导。80岁以上,两性发病率相同。在68%的病例中,卒中由梗死引起;12%由腔隙性梗死引起;15%由脑出血引起;5%由蛛网膜下腔出血引起。根据年龄,这种分布存在显著差异,蛛网膜下腔出血患者中年轻人明显占主导,而40岁以上人群中脑出血较为常见;两性梗死的比例均随年龄增加。梗死的发病率在冬季出现峰值,而短暂性脑缺血发作在夏季更为频繁。脑出血全年发病率相似。第一个月死亡率很高(第一周为12.5%,第一个月为21.5%),第一年达到30%。这些结果与西方白人人群中普遍观察到的结果相当。它们证实了出血的有限发病率(与在日本观察到的情况相反),强调了腔隙综合征的重要且常被低估的作用,以及每种机制特有的季节性变化。

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