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[卒中的管理。第戎卒中登记处的价值]

[Management of stroke. The value of the Dijon Stroke Registry].

作者信息

Giroud M, Lemesle M

机构信息

Registre Dijonnais des Accidents Vasculaires Cérébraux, Service de Neurologie, Hôpital Général, Dijon.

出版信息

Rev Epidemiol Sante Publique. 1996;44 Suppl 1:S70-7.

PMID:8935867
Abstract

Since 1985, the Stroke Registry of Dijon has performed a prospective, specific and exhaustive collection of stroke episodes occurring in patients living in the city of Dijon. The first aim of such a register is descriptive epidemiology to determine the natural history of strokes which would be impossible without this methodology. This procedure can also be used as a tool for research and evaluation. Therefore, over the past 9 years the Stroke Registry of Dijon has observed a 15% decrease of the incidence of cerebral haemorrhage, due to early diagnosis and treatment of arterial hypertension. Inversely, the incidence of cerebral infarct increased 8.5% during the same period due to the increased frequency of cardiac emboli. Mortality decreased in the same period from 22% to 15%, due to active treatments during the acute stage and to a decrease of the early severity of stroke at admission to hospital. The severity of the handicap decreased dramatically during the same period. Several case-control studies have shown the negative role of hyperglycaemia and cardiac arrhythmia on mortality in the acute stage of strokes. The role of dyslipidaemia has been evaluated in the aetiology of the different mechanisms of stroke, demonstrating the role of hypocholesterolaemia in the genesis of cerebral haemorrhage. Some interventions performed by the Registry in the population of the city of Dijon have shown that early diagnosis and treatment of transient ischemic attacks with anticoagulants may decrease the occurrence of cerebral infarction. Then, the evaluation of access to health care permitted to observe that the choice between public hospitals, private hospitals and home was dependent on age, troubles of consciousness, and severity of the neurological deficit. Therefore, the Stroke Registry of Dijon participates in improving our knowledge of the natural history of strokes, and to the evaluation of diagnostic and therapeutic strategies.

摘要

自1985年以来,第戎卒中登记处对居住在第戎市的患者发生的卒中事件进行了前瞻性、针对性且详尽的收集。这样一个登记处的首要目标是描述性流行病学,以确定卒中的自然史,没有这种方法这将是不可能的。这个程序也可以用作研究和评估的工具。因此,在过去9年里,由于对动脉高血压的早期诊断和治疗,第戎卒中登记处观察到脑出血发病率下降了15%。相反,由于心脏栓子频率增加,同期脑梗死发病率增加了8.5%。由于急性期的积极治疗以及入院时卒中早期严重程度的降低,同期死亡率从22%降至15%。同一时期残疾严重程度大幅下降。几项病例对照研究表明高血糖和心律失常在卒中急性期对死亡率有负面作用。血脂异常在卒中不同机制的病因学中的作用已得到评估,表明低胆固醇血症在脑出血发生中的作用。登记处在第戎市人群中进行的一些干预表明,用抗凝剂对短暂性脑缺血发作进行早期诊断和治疗可能会减少脑梗死的发生。然后,对获得医疗保健情况的评估发现,在公立医院、私立医院和家庭之间的选择取决于年龄、意识障碍和神经功能缺损的严重程度。因此,第戎卒中登记处参与增进我们对卒中自然史的了解,并参与诊断和治疗策略的评估。

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