Liu Shun-Ying, Huang Jin, Dong Qiao-Liang, Li Bei, Zhao Xue, Xu Rong, Yin Hong-Fang
Clinical Nursing Teaching and Research Section, The Second Xiangya Hospital, Central South University.
the affiliated hospital of Guizhou medical university.
Medicine (Baltimore). 2020 Mar;99(11):e18831. doi: 10.1097/MD.0000000000018831.
This study aimed to investigate diabetes distress, happiness, and its associated factors of patients with type 2 diabetes mellitus (T2DM) treated by different therapies, and to analyze the related impact factors. A total of 1512 patients with T2DM were randomly selected from 18 tertiary hospitals in Hunan province from January 2016 to April 2016 who has been treated with oral antidiabetics monotherapy, insulin monotherapy, and combination therapy. Use the general information questionnaire, WHO-5 (the World Health Organization 5 well-being index) and PAID (the problem areas in diabetes scale) to collect the data. There are 846 (55.95%) patients that have serious emotional disorders, and the diabetes related distress in insulin treatment group was higher than that in combination treatment group (P < .05). Happiness of T2DM patients in combination therapy was higher than oral antidiabetic drug monotherapy and insulin monotherapy (P < .05). There was a negative correlation between diabetic suffering and happiness in patients with different treatments (R ranged from -0.335 to -0.436, P < .001). Age and happiness experience could explain 14.8% of the variance. Acute and chronic complications, controlled blood glucose level, lifestyle, therapies, and school education can explain 18.3% variance. Under different therapies, the suffering and happiness of T2DM patients differed from each other. The suffering and happiness of T2DM were related to different therapies, age, complications, glycaemic control, lifestyle, school education, and so on.
本研究旨在调查接受不同治疗方法的2型糖尿病（T2DM）患者的糖尿病困扰、幸福感及其相关因素，并分析相关影响因素。2016年1月至2016年4月期间，从湖南省18家三级医院中随机选取了1512例接受口服降糖药单药治疗、胰岛素单药治疗和联合治疗的T2DM患者。使用一般信息问卷、WHO-5（世界卫生组织5项幸福指数）和PAID（糖尿病问题领域量表）收集数据。有846例（55.95%）患者存在严重情绪障碍，胰岛素治疗组的糖尿病相关困扰高于联合治疗组（P<0.05）。联合治疗的T2DM患者的幸福感高于口服降糖药单药治疗和胰岛素单药治疗（P<0.05）。不同治疗的患者中，糖尿病痛苦与幸福感之间呈负相关（R范围为-0.335至-0.436，P<0.001）。年龄和幸福体验可解释14.8%的变异。急慢性并发症、血糖控制水平、生活方式、治疗方法和学校教育可解释18.3%的变异。在不同治疗方法下，T2DM患者的痛苦和幸福感各不相同。T2DM患者的痛苦和幸福感与不同的治疗方法、年龄、并发症、血糖控制、生活方式、学校教育等有关。
