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本文引用的文献

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Disease burden and government spending on mental, neurological, and substance use disorders, and self-harm: cross-sectional, ecological study of health system response in the Americas.疾病负担和政府在精神、神经和物质使用障碍及自残方面的支出:对美洲卫生系统反应的横断面、生态研究。
Lancet Public Health. 2019 Feb;4(2):e89-e96. doi: 10.1016/S2468-2667(18)30203-2. Epub 2018 Nov 14.
2
Posttraumatic stress disorder in opioid agonist therapy: A review.阿片类药物激动剂治疗中的创伤后应激障碍:综述。
Psychol Trauma. 2018 Nov;10(6):636-642. doi: 10.1037/tra0000312. Epub 2017 Jul 31.
3
Psychological interventions for post-traumatic stress disorder and comorbid substance use disorder: A systematic review and meta-analysis.创伤后应激障碍和共病物质使用障碍的心理干预措施:系统评价和荟萃分析。
Clin Psychol Rev. 2015 Jun;38:25-38. doi: 10.1016/j.cpr.2015.02.007. Epub 2015 Mar 3.
4
Comorbid posttraumatic stress disorder and opiate addiction: a literature review.创伤后应激障碍与阿片类药物成瘾共病:文献综述。
J Addict Dis. 2013;32(2):168-79. doi: 10.1080/10550887.2013.795467.
5
Opioid agonist treatments and heroin overdose deaths in Baltimore, Maryland, 1995-2009.马里兰州巴尔的摩市 1995-2009 年阿片类激动剂治疗与海洛因过量死亡情况。
Am J Public Health. 2013 May;103(5):917-22. doi: 10.2105/AJPH.2012.301049. Epub 2013 Mar 14.
6
Prevalence of post-traumatic stress disorder among patients with substance use disorder: it is higher than clinicians think it is.物质使用障碍患者创伤后应激障碍的患病率:高于临床医生认为的患病率。
Eur J Psychotraumatol. 2012;3. doi: 10.3402/ejpt.v3i0.17734. Epub 2012 Aug 8.

创伤后应激障碍与阿片类药物使用:干预和政策的影响。

PTSD and opioid use: implications for intervention and policy.

机构信息

British Columbia Centre for Substance Use, 400-1045 Howe Street, Vancouver, BC, V6Z 2A9, Canada.

Department of Medicine, University of British Columbia, St. Paul's Hospital, 608-1081 Burrard Street, Vancouver, BC, V6Z 1Y6, Canada.

出版信息

Subst Abuse Treat Prev Policy. 2020 Mar 16;15(1):22. doi: 10.1186/s13011-020-00264-8.

DOI:10.1186/s13011-020-00264-8
PMID:32178693
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7077145/
Abstract

BACKGROUND

North America remains in the midst of an escalating opioid overdose epidemic, largely driven by the influx of synthetic opioids such a fentanyl and related analogues. High rates of mental illness among substance-using populations have been well documented; in particular, opioid-using individuals suffer from high rates of PTSD. Despite the devastating disease burden of both PTSD and OUD, especially within the context of the current opioid overdose epidemic, treatment options and outcomes remain suboptimal.

MAIN BODY

Comorbid PTSD-OUD is often complex and inextricably intertwined, thereby impeding effective diagnosis, assessment and early intervention. Best outcomes occur when treatment addresses both comorbidities simultaneously, known as parallel or integrative approaches. Despite these findings, affected individuals often do not receive adequate or equitable access to healthcare. The WHO recommends that public spending for both mental and physical aspects of healthcare be equitable to the burden of disease. Despite these recommendations mental healthcare services remain chronically underfunded in Canada. The Mental Health Parity Act is a call for the Canadian government to implement equitable public spending on all aspects of healthcare. Furthermore, prohibitory legislative practices serve to marginalize substance-using populations thereby increasing the likelihood of exposure to traumatic violence and other associated harms.

CONCLUSION

Efforts are now needed to address regulatory drug-use frameworks and public healthcare policies that perpetuate these inequalities. Alternative regulatory frameworks for drugs and mental health parity should be implemented and evaluated in an effort to reduce violence, trauma and ultimately opioid-related overdose deaths.

摘要

背景

北美仍处于不断升级的阿片类药物过量流行之中,主要是由芬太尼和相关类似物等合成阿片类药物的涌入所驱动。有大量文献记录了物质使用人群中的高精神疾病发病率;特别是,阿片类药物使用者患有 PTSD 的比例很高。尽管 PTSD 和 OUD 的疾病负担都很严重,尤其是在当前阿片类药物过量流行的背景下,治疗选择和结果仍然不理想。

主要内容

并发 PTSD-OUD 通常很复杂且不可分割地交织在一起,从而阻碍了有效的诊断、评估和早期干预。当治疗同时针对两种共病时,效果最佳,称为平行或综合方法。尽管有这些发现,但受影响的个人往往无法获得足够或公平的医疗保健。世界卫生组织建议,公共支出应与精神和身体两方面的医疗保健负担相平衡。尽管有这些建议,加拿大的精神保健服务仍然长期资金不足。《精神健康平等法案》呼吁加拿大政府在医疗保健的各个方面实现公平的公共支出。此外,禁止性立法做法使药物使用者群体边缘化,从而增加了接触创伤暴力和其他相关伤害的可能性。

结论

现在需要努力解决监管药物使用框架和公共医疗保健政策,以消除这些不平等。应实施替代的药物和精神健康平等监管框架,并对其进行评估,以减少暴力、创伤,最终减少与阿片类药物相关的过量死亡。