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院外心脏骤停机械胸外按压装置:一项全国范围的观察性研究。

Mechanical Chest Compression Device for Out-Of-Hospital Cardiac Arrest: A Nationwide Observational Study.

机构信息

Department of Emergency Medicine, Chonnam National University Hospital, Dong-gu, Gwangju, Republic of Korea.

Department of Emergency Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.

出版信息

J Emerg Med. 2020 Mar;58(3):424-431. doi: 10.1016/j.jemermed.2019.11.022. Epub 2020 Mar 13.

Abstract

BACKGROUND

There are few studies on the use of a mechanical chest compression (meCC) device during transport in patients with out-of-hospital cardiac arrest (OHCA).

OBJECTIVE

The aim of our study was to compare the performance of an meCC device with that of manual chest compression during transport after OHCA.

METHODS

This study used data from the national cardiac arrest registry of patients with OHCA of presumed cardiac etiology. The primary exposure was the use of an meCC device by an Emergency Medical Services provider while transporting a patient to the emergency department. The primary endpoint was good cerebral performance category at discharge. We compared survival and neurologic outcomes between an meCC device group and a manual chest compression group. We also performed an interaction analysis to assess changes in study outcomes of meCC device use by the initial electrocardiogram (ECG) and transport time interval (TTI).

RESULTS

Among 30,021 adult patients after OHCA with presumed cardiac etiology, an meCC device was used in 2357 (7.6%). After adjustment for possible confounders, there were no significant differences with respect to good neurologic recovery in the outcomes of patients who were treated with an meCC device and those who received manual chest compression (adjusted odds ratio [AOR] 0.66; 95% confidence interval [CI] 0.43-1.02) and survival to discharge (AOR 0.83; 95% CI 0.64-1.06). In the interaction model, the AOR of the meCC device study outcome did not interact with the initial ECG and TTI.

CONCLUSIONS

The meCC device did not show better study outcomes than manual compression.

摘要

背景

在院外心脏骤停(OHCA)患者的转运过程中,使用机械胸外按压(meCC)设备的研究较少。

目的

本研究旨在比较 OHCA 患者转运过程中使用 meCC 设备与手动胸外按压的效果。

方法

本研究使用了全国 OHCA 伴有疑似心源性病因患者的心脏骤停登记数据库中的数据。主要暴露因素为急救医疗服务提供者在将患者转运至急诊室的过程中使用 meCC 设备。主要终点是出院时的良好脑功能预后。我们比较了 meCC 设备组和手动胸外按压组的生存和神经功能结局。我们还进行了交互分析,以评估 meCC 设备使用对初始心电图(ECG)和转运时间间隔(TTI)的研究结局的影响。

结果

在 30021 例伴有疑似心源性病因的成年 OHCA 患者中,有 2357 例(7.6%)使用了 meCC 设备。在调整了可能的混杂因素后,使用 meCC 设备的患者与接受手动胸外按压的患者在神经功能恢复良好的结局(调整后的优势比 [AOR] 0.66;95%置信区间 [CI] 0.43-1.02)和出院时的生存(AOR 0.83;95% CI 0.64-1.06)方面无显著差异。在交互模型中,meCC 设备研究结局的 AOR 与初始 ECG 和 TTI 无交互作用。

结论

meCC 设备的研究结局并不优于手动按压。

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