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亚洲原发性免疫缺陷病的现状与前景

Current status and prospects of primary immunodeficiency diseases in Asia.

作者信息

Pilania Rakesh Kumar, Chaudhary Himanshi, Jindal Ankur Kumar, Rawat Amit, Singh Surjit

机构信息

Allergy Immunology Unit, Department of Pediatrics, Advanced Pediatrics Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India.

出版信息

Genes Dis. 2019 Sep 12;7(1):3-11. doi: 10.1016/j.gendis.2019.09.004. eCollection 2020 Mar.

DOI:10.1016/j.gendis.2019.09.004
PMID:32181271
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7063407/
Abstract

Primary Immunodeficiency Diseases (PIDs) are increasingly being reported across the World. Several advances have been made in the diagnostic and therapeutic research related to PIDs. With increasing awareness, the field of PIDs has rapidly evolved in Asia as well. In this review, we summarize the progress that has been made in the field of PIDs in Asian countries; major limitations and challenges faced by the clinicians working in this field in Asia; difference in spectrum of PIDs in Asia from rest of the World; current state of diagnostic and treatment facilities available in various countries in Asia and the future prospects of these diseases in the continent.

摘要

原发性免疫缺陷病(PIDs)在全球的报告日益增多。在与PIDs相关的诊断和治疗研究方面已经取得了一些进展。随着认识的提高,PIDs领域在亚洲也迅速发展。在这篇综述中,我们总结了亚洲国家在PIDs领域取得的进展;亚洲从事该领域工作的临床医生面临的主要限制和挑战;亚洲PIDs谱系与世界其他地区的差异;亚洲各国现有诊断和治疗设施的现状以及这些疾病在该大陆的未来前景。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a6d/7063407/b83fdffd8f72/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a6d/7063407/b83fdffd8f72/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a6d/7063407/b83fdffd8f72/gr1.jpg

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2
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Asia Pac Allergy. 2018 Oct 30;8(4):e42. doi: 10.5415/apallergy.2018.8.e42. eCollection 2018 Oct.
3
Fourth Update on the Iranian National Registry of Primary Immunodeficiencies: Integration of Molecular Diagnosis.
在儿童医院诊断出的不同类型原发性免疫缺陷疾病的谱系。
Pak J Med Sci. 2025 Feb;41(2):569-574. doi: 10.12669/pjms.41.2.9511.
4
Rare and heterogeneous manifestations of leucocyte adhesion deficiency type 1: report of two cases with diagnostic dilemmas and novel ITGB2 mutation.1型白细胞黏附缺陷症的罕见及异质性表现:两例诊断难题及新型ITGB2突变报告
Allergy Asthma Clin Immunol. 2023 May 2;19(1):36. doi: 10.1186/s13223-023-00786-3.
5
Primary immunodeficiencies (PID) Life Index in Southeast Asia: A comparative analysis of PID Principles of Care (PoC).原发性免疫缺陷病(PID)在东南亚的生命指数:PID 护理原则(PoC)的比较分析。
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6
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