Jindal Ankur Kumar, Pilania Rakesh Kumar, Rawat Amit, Singh Surjit
Allergy Immunology Unit, Advanced Pediatrics Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Front Immunol. 2017 Jun 19;8:714. doi: 10.3389/fimmu.2017.00714. eCollection 2017.
Primary immunodeficiency disorders (PIDs) are a group of genetic defects characterized by abnormalities of one or more components of the immune system. While there have been several advances in diagnosis, management, and research in the field of PIDs, they continue to remain underdiagnosed, especially in the less affluent countries. Despite several limitations and challenges, India has advanced significantly in the field of PIDs in the last few years. In this review, we highlight the progress in the field of PIDs in India over the last 25 years, the difficulties faced by clinicians across the country, the current state of PIDs in India and the future prospects.
原发性免疫缺陷病(PIDs)是一组遗传性缺陷疾病,其特征为免疫系统的一个或多个组成部分存在异常。尽管原发性免疫缺陷病领域在诊断、管理和研究方面取得了多项进展,但这些疾病仍未得到充分诊断,尤其是在较贫困国家。尽管存在诸多限制和挑战,但印度在过去几年里在原发性免疫缺陷病领域取得了显著进展。在本综述中,我们重点介绍了印度在过去25年里原发性免疫缺陷病领域的进展、全国临床医生面临的困难、印度原发性免疫缺陷病的现状以及未来前景。