Zhiznevskaia N G, Makarenko V S
Vopr Med Khim. 1988 Sep-Oct;34(5):37-9.
Acute kidney insufficiency was simulated in rats by means of intramuscular administration of glycerol. Intensity of protein biosynthesis and content of proteins were increased, while their catabolism was decreased in kidney under these conditions. At the same time, half-life and a period of the proteins turnover were elongated, whereas the rate of their substitution was decreased.
通过肌肉注射甘油在大鼠中模拟急性肾功能不全。在这些条件下，肾脏中蛋白质生物合成的强度和蛋白质含量增加，而其分解代谢减少。同时，蛋白质周转的半衰期和周期延长，而其替代率降低。
