Dolzhanskiĭ A M, Kuznetsov S V, Bugaeva N P, Mikhaĭlova M I, Ketiladze E S
Vopr Virusol. 1988 Sep-Oct;33(5):561-4.
Electron microscopy and morphometry were used to study liver biopsies from 22 patients with chronic active hepatitis. On the basis of clinico-morphological data 9 patients were diagnosed as having chronic active delta hepatitis and 13 patients chronic active hepatitis B. The studies indicate more marked involvement of hepatocytes in chronic delta hepatitis as compared with chronic hepatitis of HB virus etiology. Morphometric methods allow quantitation of the degree of manifestations of hepatocyte ultrastructural changes in the two groups of patients.
采用电子显微镜和形态测量学方法对22例慢性活动性肝炎患者的肝活检组织进行研究。根据临床形态学资料,9例患者被诊断为慢性活动性丁型肝炎,13例患者为慢性活动性乙型肝炎。研究表明,与乙型肝炎病毒病因所致的慢性肝炎相比,慢性丁型肝炎患者的肝细胞受累更为明显。形态测量学方法能够对两组患者肝细胞超微结构变化的表现程度进行定量分析。