语境相关的免疫应答解释了胰腺癌的免疫抵抗。
Context-Dependent Immune Responses Explain Pancreatic Cancer Immunoresistance.
机构信息
Department of Surgery, University of Michigan, Ann Arbor, MI, USA; Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA.
Department of Surgery, University of Michigan, Ann Arbor, MI, USA; Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA; Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI, USA.
出版信息
Cancer Cell. 2020 Mar 16;37(3):261-263. doi: 10.1016/j.ccell.2020.02.010.
Immunotherapy is standard of care for many malignancies, including non-small cell lung cancer, but its benefits have not extended to pancreatic cancer. In this issue of Cancer Cell, DeNardo and colleagues investigate the differences in immune response in lung and pancreas and potential approaches to overcome immunoresistance in the latter.
免疫疗法是许多恶性肿瘤（包括非小细胞肺癌）的标准治疗方法，但它的益处尚未扩展到胰腺癌。在本期《癌细胞》杂志中，DeNardo 及其同事研究了肺部和胰腺中免疫反应的差异，以及克服后者免疫抵抗的潜在方法。
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