Department of Otolaryngology-Head and Neck Surgery, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233, China; Shanghai Key Laboratory of Sleep Disordered Breathing, Shanghai 200233, China; Otolaryngology Institute of Shanghai Jiao Tong University, Shanghai 200233, China.
Department of Otolaryngology-Head and Neck Surgery, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233, China; Shanghai Key Laboratory of Sleep Disordered Breathing, Shanghai 200233, China; Otolaryngology Institute of Shanghai Jiao Tong University, Shanghai 200233, China.
Am J Otolaryngol. 2020 May-Jun;41(3):102450. doi: 10.1016/j.amjoto.2020.102450. Epub 2020 Feb 27.
Nasal septal deviation (NSD) has a significant impact on patients' quality of life; however, there have been limited studies examining the psychological status of NSD patients. In this study, symptoms of depression and anxiety were investigated between NSD patients and controls using a self-report questionnaire.
A case-control study design was used to evaluate the psychological burden of NSD in patients who visited the general hospital. The control group comprised of ENT outpatients without a history of chronic nasal disease. The Zung Self-rating Anxiety/Depression Scale (SDS/SAS) was used to evaluate the prevalence and severity of anxiety and depression between the NSD and control group.
Seventy-six patients with NSD and 79 control patients were enrolled in the study. We found that depression and anxiety, as well as the co-morbidity of depression with anxiety, were more common in the NSD group in comparison to the control (39.5% vs 22.8%, p = 0.025; 38.2% vs 15.2%, p = 0.001; and 27.6% vs 11.4%, p = 0.011, respectively). The average SDS and SAS score was higher in NSD patients compared to controls (SDS: 49.7 ± 13.1 vs 45.2 ± 10.4, p = 0.019 and SAS: 48.1 ± 11.6 vs 41.3 ± 9.3, p < 0.001, respectively), and NSD patients were found to have more severe levels of anxiety and depression.
Depression and anxiety are more common and severe in patients with NSD. Therefore, psychological distress should be taken into consideration during the diagnostic and therapeutic process for patients with NSD.
鼻中隔偏曲（NSD）显著影响患者的生活质量；然而，目前仅有少数研究探讨 NSD 患者的心理状态。本研究采用自报问卷的方式，比较 NSD 患者与对照组的抑郁和焦虑症状。
采用病例对照研究设计，评估综合医院 NSD 患者的心理负担。对照组为无慢性鼻部疾病病史的耳鼻喉科门诊患者。采用zung 自评焦虑/抑郁量表（SDS/SAS）评估 NSD 组与对照组之间焦虑和抑郁的发生率和严重程度。
本研究共纳入 76 例 NSD 患者和 79 例对照组患者。我们发现，与对照组相比，NSD 组的抑郁和焦虑，以及抑郁伴焦虑的共病更为常见（39.5%比 22.8%，p=0.025；38.2%比 15.2%，p=0.001；27.6%比 11.4%，p=0.011）。与对照组相比，NSD 患者的 SDS 和 SAS 平均评分更高（SDS：49.7±13.1 比 45.2±10.4，p=0.019 和 SAS：48.1±11.6 比 41.3±9.3，p<0.001），且 NSD 患者的焦虑和抑郁更为严重。
NSD 患者更常出现且更严重的抑郁和焦虑。因此，在 NSD 患者的诊断和治疗过程中，应考虑心理困扰。
