Department of Otolaryngology, Head and Neck Surgery, The First Hospital of Jilin University, No. 1 Xinmin Street, Changchun, 130000, Jilin Province, China.
Sci Rep. 2024 Nov 21;14(1):28855. doi: 10.1038/s41598-024-80377-3.
The value of endoscopic septoplasty for patients with deviated nasal septum and allergic rhinitis has not been systematically summarized. This study aims to assess the impact of surgical intervention on quality of life through a meta-analysis.
We conducted a comprehensive search of PubMed, CNKI, EMBASE, and the Cochrane Library for studies on the treatment of patients with deviated nasal septum and allergic rhinitis up to 2024. Studies that were duplicates, lacked full text, had incomplete data, or involved animal experiments, commentaries, or systematic reviews were excluded. Meta-analysis was performed using STATA 16.0.
The total nasal symptom score (TNSS) in patients who received endoscopic surgery was considerably reduced compared to those treated with spray therapy alone, indicating a significant improvement (SMD = -21.29, 95% CI: -26.26, -116.33). Classic symptoms of allergic rhinitis, including rhinorrhea (SMD=-9.97, 95% CI: -16.97, -2.98), nasal obstruction (SMD=-27.25, 95% CI: -41.12, -13.38), nasal itching (SMD=-10.32, 95% CI: -13.16, -7.48), and sneezing (SMD=-12.66, 95% CI: -14.99, -10.34), showed significant improvement. There was no significant difference in the incidence of complications between the two treatments (OR = 1.01, 95% CI: 0.49, 2.10).
Patients with a deviated nasal septum and allergic rhinitis benefit more from septoplasty. However, the procedure should be performed cautiously by experienced clinicians, taking into account the specific condition of the nasal septum.
鼻中隔偏曲合并变应性鼻炎患者行内镜下鼻中隔成形术的价值尚未得到系统总结。本研究旨在通过meta 分析评估手术干预对生活质量的影响。
我们全面检索了PubMed、中国知网(CNKI)、EMBASE 和 Cochrane 图书馆中截至 2024 年治疗鼻中隔偏曲合并变应性鼻炎患者的研究。排除重复研究、缺乏全文、数据不完整或涉及动物实验、评论或系统评价的研究。采用 STATA 16.0 进行 meta 分析。
与单独接受喷雾治疗的患者相比,接受内镜手术的患者的总鼻症状评分(TNSS)显著降低,表明有显著改善(SMD=-21.29,95%CI:-26.26,-116.33)。变应性鼻炎的典型症状,包括流涕(SMD=-9.97,95%CI:-16.97,-2.98)、鼻塞(SMD=-27.25,95%CI:-41.12,-13.38)、鼻痒(SMD=-10.32,95%CI:-13.16,-7.48)和打喷嚏(SMD=-12.66,95%CI:-14.99,-10.34)均有显著改善。两种治疗方法的并发症发生率无显著差异(OR=1.01,95%CI:0.49,2.10)。
鼻中隔偏曲合并变应性鼻炎患者行鼻中隔成形术获益更多。然而,经验丰富的临床医生应谨慎操作,同时考虑鼻中隔的具体情况。