Bąk Ewelina, Marcisz-Dyla Ewa, Młynarska Agnieszka, Sternal Danuta, Kadłubowska Monika, Marcisz Czesław
Faculty of Health Sciences, University of Bielsko-Biala, Bielsko-Biala, Poland.
Department of Anxiety Disorders, Hospital of Ministry of Internal Affairs, Katowice, Poland.
Patient Prefer Adherence. 2020 Mar 3;14:443-454. doi: 10.2147/PPA.S237767. eCollection 2020.
Patients with diabetes are at increased risk of developing depression. The aim of the study was to determine the occurrence of depressive symptoms in patients with type 1 (T1DM) and type 2 diabetes (T2DM), including the association with different independent sociodemographic and clinical variables.
The studies were carried out on 618 people, including 115 patients with T1DM and 215 patients with T2DM and 288 people without diabetes constituting two control groups. Subjects were characterized in terms of sociodemographic, clinical and biochemical aspects, and the occurrence of depressive symptoms using Beck Depression Inventory (BDI) was determined. In the logistic regression analysis, the correlations between BDI score and with independent variables such as sex, age, body mass index, duration of diabetes, HbA1c level, diabetic complications and mean arterial pressure were examined.
The mean BDI score was significantly higher in women and men with T1DM and T2DM compared to controls. In diabetic patients, depressive symptoms occurred more often in women than in men. Among patients with T1DM, the incidence of depressive symptoms was 17.5% of the women and 8.6% of the men and in patients with T2DM, the incidence of depressive symptoms was revealed in 28.9% of the women and in 19.8% of the men. In patients with T1DM and T2DM, the occurrence of depressive symptoms increases with age, HbA1c level and complications, and the risk of depressive symptoms turned out to be almost three times higher in women than in men with T2DM.
The prevalence of depressive symptoms in diabetic patients is higher than in non-diabetics. Depressive symptoms account for 13% of the patients with T1DM and 24.7% of the patients with T2DM. The risk of depressive symptoms in T1DM and T2DM increases with age, HbA1c level and the presence of complications, and it is gender-related in T2DM only.
糖尿病患者患抑郁症的风险增加。本研究的目的是确定1型糖尿病（T1DM）和2型糖尿病（T2DM）患者抑郁症状的发生率，包括与不同独立社会人口统计学和临床变量的关联。
对618人进行了研究，其中包括115例T1DM患者、215例T2DM患者以及288名无糖尿病者，后者构成两个对照组。从社会人口统计学、临床和生化方面对受试者进行了特征描述，并使用贝克抑郁量表（BDI）确定了抑郁症状的发生率。在逻辑回归分析中，研究了BDI评分与性别、年龄、体重指数、糖尿病病程、糖化血红蛋白水平、糖尿病并发症和平均动脉压等自变量之间的相关性。
与对照组相比，T1DM和T2DM的女性和男性患者的平均BDI评分显著更高。在糖尿病患者中，女性比男性更常出现抑郁症状。在T1DM患者中，女性抑郁症状的发生率为17.5%，男性为8.6%；在T2DM患者中，女性抑郁症状的发生率为28.9%，男性为19.8%。在T1DM和T2DM患者中，抑郁症状的发生率随年龄、糖化血红蛋白水平和并发症的增加而升高，且T2DM女性出现抑郁症状的风险几乎是男性的三倍。
糖尿病患者抑郁症状的患病率高于非糖尿病患者。抑郁症状在T1DM患者中占13%，在T2DM患者中占24.7%。T1DM和T2DM患者抑郁症状的风险随年龄、糖化血红蛋白水平和并发症的出现而增加，且仅在T2DM中与性别相关。
