Peng Zihe, Yu Yuelin, Wei Wei, Hou Yongchun, Sun Zhenyu, Wang Ying, Zhang Lin, Zhou Ying, Wang Qian, Cai Yong
School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
Putuo District Center for Disease Control and Prevention, Shanghai, People's Republic of China.
Patient Prefer Adherence. 2020 Mar 5;14:507-515. doi: 10.2147/PPA.S234041. eCollection 2020.
The purpose of this article was to examine the validity and reliability of the LifeWindows Information-Motivation-Behavioral Skills Antiretroviral Therapy (ART) Adherence Questionnaire (LW-IMB-AAQ) among HIV+ patients in Shanghai.
We surveyed 426 HIV+ patients in Shanghai's Putuo District to examine the validity and reliability of the questionnaire. The questionnaire includes self-reported demographic characteristics, the modified version of the Community Programs for Clinical Research on AIDS Antiretroviral Medication Self-Report (CPCRA) and LW-IMB-AAQ. CPCRA was used to calculate ART adherence. LW-IMB-AAQ, including the information section, the motivation section and the behavioral skills section, was used to analyze patients' ART adherence. We analyzed data by means, standard deviation, critical ratio, and item-total correlation. Reliability was assessed by internal consistency, split-half reliability, and test-retest reliability. Validity was assessed by exploratory factor analysis (EFA), confirmatory factor analysis (CFA), convergent validity and discriminant validity.
Item analysis showed that except for motivation item 1, all items were acceptable. For reliability, Cronbach's alpha coefficients for the three sections and the total scale were all higher than 0.7, with interclass correlation coefficients (ICC) all higher than 0.6 (p<0.001). The Spearman-Brown coefficient for the total scale was 0.825. For validity, results showed that the information section could be divided into two subscales, motivation section and behavioral skills section could be divided into three and two subscales, respectively. The final model demonstrated good validity (p=0.471, /df=0.960, CFI=1.000, GFI=0.994 and RMSEA<0.001) without motivation item 4.
Excluding motivation items 1 and 4, the LifeWindows Information-Motivation-Behavioral Skills ART Adherence Questionnaire (LW-IMB-AAQ) demonstrated good validity and reliability among HIV+ patients in Shanghai.
本文旨在检验《生命之窗信息 - 动机 - 行为技能抗逆转录病毒疗法（ART）依从性问卷》（LW - IMB - AAQ）在上海HIV阳性患者中的有效性和可靠性。
我们对上海普陀区的426名HIV阳性患者进行了调查，以检验该问卷的有效性和可靠性。问卷包括自我报告的人口统计学特征、艾滋病抗逆转录病毒药物临床研究社区项目自我报告（CPCRA）的修订版以及LW - IMB - AAQ。CPCRA用于计算ART依从性。LW - IMB - AAQ包括信息部分、动机部分和行为技能部分，用于分析患者的ART依从性。我们通过均值、标准差、临界比率和项目 - 总分相关性来分析数据。通过内部一致性、分半信度和重测信度来评估信度。通过探索性因素分析（EFA）、验证性因素分析（CFA）、收敛效度和区分效度来评估效度。
项目分析表明，除动机项目1外，所有项目均可接受。在信度方面，三个部分和总量表的克朗巴哈α系数均高于0.7，组内相关系数（ICC）均高于0.6（p<0.001）。总量表的斯皮尔曼 - 布朗系数为0.825。在效度方面，结果表明信息部分可分为两个子量表，动机部分和行为技能部分分别可分为三个和两个子量表。最终模型显示出良好的效度（p = 0.471，χ²/df = 0.960，CFI = 1.000，GFI = 0.994且RMSEA<0.001），不包括动机项目4。
排除动机项目1和4后，《生命之窗信息 - 动机 - 行为技能ART依从性问卷》（LW - IMB - AAQ）在上海HIV阳性患者中显示出良好的有效性和可靠性。
