阿根廷菊科植物提取物的抗活性

Anti- Activity of Extracts from Argentinean Asteraceae Species.

作者信息

Selener Mariana G, Elso Orlando, Grosso Carla, Borgo Jimena, Clavin María, Malchiodi Emilio L, Cazorla Silvia I, Flavia Flavia, Sülsen Valeria P

机构信息

Cátedra de Farmacognosia, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Buenos Aires, Argentina.

Instituto de Química y Metabolismo del Fármaco (IQUIMEFA) (UBA-CONICET), Buenos Aires, Argentina.

出版信息

Iran J Pharm Res. 2019 Fall;18(4):1854-1861. doi: 10.22037/ijpr.2019.14491.12430.

DOI:10.22037/ijpr.2019.14491.12430

PMID:32184852

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7059055/

Abstract

The anti- activity of extracts from 13 Argentinean Asteraceae species was determined. Dichloromethane and methanol extracts of , , and were evaluated against epimastigotes, , , , , and dichloromethane extracts showed trypanocidal activity with inhibitions higher than 60% at a concentration of 10 µg/mL. The methanol extracts of and were the most active with inhibitions of 70.1 and 77.7%, respectively at 10 µg/mL. The chromatographic profiles of the most active extracts showed bands and major peaks that could be attributed to flavonoids and terpenoid compounds.

摘要

测定了13种阿根廷菊科植物提取物的抗活性。对来自[具体植物名称1]、[具体植物名称2]和[具体植物名称3]的二氯甲烷和甲醇提取物进行了评估，以对抗上鞭毛体，[列举的几种寄生虫名称]，[具体植物名称1]、[具体植物名称2]和[具体植物名称3]的二氯甲烷提取物表现出杀锥虫活性，在浓度为10μg/mL时抑制率高于60%。[具体植物名称4]和[具体植物名称5]的甲醇提取物活性最高，在10μg/mL时抑制率分别为70.1%和77.7%。活性最高的提取物的色谱图显示出可能归因于黄酮类和萜类化合物的条带和主要峰。