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寻找听神经瘤的诊断策略。300例听神经瘤患者的研究结果。

Diagnostic strategies in search for acoustic neuromas. Findings in 300 acoustic neuroma patients.

作者信息

Thomsen J, Tos M

机构信息

University ENT-department, Gentofte Hospital, Hellerup, Denmark.

出版信息

Acta Otolaryngol Suppl. 1988;452:16-25. doi: 10.3109/00016488809124990.

Abstract

The diagnostic findings in 300 patients with acoustic neuromas are reported. Because of a centralized treatment of acoustic neuromas, we have a uniform work-up of all the patients, which enables us to make a non-selected comparison of the diagnostic efficiency of the various tests. Diagnostic dilemmas in patients with normal hearing, anakusis, normal auditory brainstem recordings, normal vestibular function and normal tomography of the internal acoustic meatus are discussed. In patients with hearing better than 80 dB, a normal ABR, the presence of recruitment and a normal caloric reaction can exclude the presence of a tumour, making tomography superfluous. In patients with poor hearing, the need for tomography is imperative. We perform CT if two procedures among the following produce tumour-positive results: ABR, recruitment tests, caloric test, and tomography. Those who have only one tumour-positive finding at the screening are re-examined after one year. If, even with contrast enhancement, CT proves negative, we continue to perform air CT. Only then do we know for sure whether the patient has a tumour or not. An advantage with using many tests for the same physiological function is that they complement each other, though, on the other hand this often adds to the confusion. With fewer tests, the confusion is reduced, but the requirements regarding technical quality must be very stringent. ABR, the Metz recruitment test and tomography are purely objective, while the caloric test is subjective on the part of the investigator. The Hallpike procedure, however, has stood the test of time in separating pathologic from normal.

摘要

报告了300例听神经瘤患者的诊断结果。由于听神经瘤采用集中治疗,我们对所有患者进行了统一的检查,这使我们能够对各种检查的诊断效率进行无选择性的比较。讨论了听力正常、失聪、听觉脑干记录正常、前庭功能正常以及内耳道断层扫描正常的患者的诊断难题。对于听力优于80分贝、ABR正常、存在重振现象且冷热试验正常的患者,可以排除肿瘤的存在,断层扫描就没有必要了。对于听力较差的患者,进行断层扫描是必不可少的。如果以下检查中的两项结果为肿瘤阳性,我们就进行CT检查:ABR、重振试验、冷热试验和断层扫描。那些在筛查中只有一项肿瘤阳性结果的患者,一年后重新检查。即使增强扫描后CT结果为阴性,我们仍继续进行气脑CT检查。只有到那时我们才能确定患者是否患有肿瘤。对同一生理功能使用多种检查的一个优点是它们可以相互补充,不过,另一方面这往往会增加混淆。检查项目越少,混淆就越少,但对技术质量的要求必须非常严格。ABR、梅茨重振试验和断层扫描是完全客观的,而冷热试验在检查者方面是主观的。然而,霍尔派克检查法在区分病理性与正常情况方面经受住了时间的考验。

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