Li S S, Wang L, Li A H
Zhenjiang Municipal Center for Disease Control and Prevention, Jiangsu Province, Zhenjiang 212004, China.
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2019 Oct 9;32(1):83-86. doi: 10.16250/j.32.1374.2019137.
To understand the epidemic trend of soil-transmitted nematodiasis in Zhenjiang City from 2006 to 2018, so as to provide evidence for formulating targeted control measures.
The permanent residents at ages of 3 years and greater and the immigrants who had lived in Zhenjiang City for more than one year were selected as the study subjects. Fecal samples were collected, and the soil-transmitted nematode eggs were detected in fecal samples with the modified Kato-Katz technique (three smears from one stool sample), while the children at ages of 12 years and lower were tested for eggs using the adhesive cellophane-tape perianal swab method. The prevalence and intensity of parasitic infections were estimated in Zhenjiang City each year from 2006 to 2018, and the data pertaining to the deworming for soil-transmitted nematode infections were collected during the study period.
A total of 202 880 person-times were subjected to stool examinations in Zhenjiang City from 2006 to 2018, and 946 persons were detected with soil-transmitted nematode infections, with a mean prevalence of 0.47%. The overall prevalence of human soil-transmitted nematode infections appeared a decline tendency ( < 0.01), with a reduction from 1.10% in 2006 to 0.11% in 2018, and there was a region-specific overall prevalence ( < 0.01), with the highest prevalence seen in Runzhou District (1.65%) and the lowest detected in New District (0.04%). The mean prevalence of human , hookworm and infections was 0.33%, 0.09% and 0.04% in Zhenjiang City, respectively, and showed a decline tendency year by year from 2006 to 2018 ( < 0.01). Among all infections, mild infections were predominant. During the period from 2006 through 2018, a total of 45 427 children were examined in Zhenjiang City from 2006 to 2018, and 145 children were positive for infections, with a mean prevalence of 0.32%. The prevalence of infections decreased from 1.33% in 2006 to 0.22% in 2018 in children, and the overall prevalence appeared a decline tendency ( < 0.01). A single parasite infection was predominant in soil-transmitted nematode infections (97.46%), and mixed infection of two parasites were mainly detected before 2007. A total of 535 089 person-times received deworming in Zhenjiang City from 2006 to 2018, and the rate of adverse events was 0.002%.
Currently, the soil-transmitted nematode infection is at a low level in Zhenjiang City, and the overall prevalence of soil-transmitted nematode infections shows a decline tendency year by year. The surveillance and health education of soil-transmitted nematodiasis should be further intensified to consolidate the control achievements.
了解2006 - 2018年镇江市土源性线虫病流行趋势，为制定针对性防控措施提供依据。
选取3岁及以上常住人口和在镇江市居住1年以上的外来人员作为研究对象。采集粪便样本，采用改良加藤厚涂片法（一粪三检）检测粪便中土源性线虫卵，12岁及以下儿童采用透明胶纸肛拭法检测虫卵。估算2006 - 2018年镇江市每年寄生虫感染率和感染度，并收集研究期间土源性线虫感染驱虫治疗相关数据。
2006 - 2018年镇江市共检查202 880人次，查出土源性线虫感染者946人，平均感染率为0.47%。人群土源性线虫总体感染率呈下降趋势（P<0.01），由2006年的1.10%降至2018年的0.11%，且存在地区差异（P<0.01），润州区感染率最高（1.65%），新区最低（0.04%）。镇江市蛔虫、钩虫和鞭虫平均感染率分别为0.33%、0.09%和0.04%，2006 - 2018年呈逐年下降趋势（P<0.01）。各种感染中以轻度感染为主。2006 - 2018年镇江市共检查儿童45 427人，查出蛲虫感染者145人，平均感染率为0.32%。儿童蛲虫感染率由2006年的1.33%降至2018年的0.22%，总体感染率呈下降趋势（P<0.01）。土源性线虫感染以单虫感染为主（97.46%），2007年前主要为两种寄生虫混合感染。2006 - 2018年镇江市共535 089人次接受驱虫治疗，不良反应发生率为0.002%。
目前镇江市土源性线虫感染处于低水平，土源性线虫总体感染率呈逐年下降趋势。应进一步加强土源性线虫病监测和健康教育，巩固防控成果。
