Moussavi Elnaz, Houssaini Mohammad, Salari Nader, Hemmati Mahvan, Abdullahi Ahmad, Khaleghi Ali Asghar, Shohaimi Shamarina, Mohammadi Masoud
Student research committee, Gerash University of Medical Sciences, Gerash, Iran.
Department of Biostatistics, School of Health, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Parasite Epidemiol Control. 2023 Jul 13;22:e00315. doi: 10.1016/j.parepi.2023.e00315. eCollection 2023 Aug.
Parasitic infections are among the most common diseases worldwide, and enterobiasis is a well-known type of parasitic infection in children. Given the existence of several reports on the prevalence of in different provinces of Iran and the heterogeneity of the reported prevalence data, this study aims to investigate the overall prevalence of among children in Iran through a systematic review and meta-analysis.
This systematic review and meta-analysis study involved a comprehensive search of several databases, including PubMed, ScienceDirect, SID, and Google Scholar, focusing on cross-sectional studies that examined the prevalence of infection in Iranian children. The identified studies were entered into the EndNote software for review. The quality of observational studies was evaluated using the STROBE checklist. The information extracted from the studies was entered into the Comprehensive Meta-analysis (CMA, Version 2) software. Heterogeneity among the studies was analyzed using the I test, and publication bias was assessed using the Egger test and funnel plot.
A total of 51 studies, with a sample size of 46,070 children, were included in the review. Using the random effects method, the overall prevalence of among children in Iran was determined to be 6.7% (95%CI: 5.2-8.6). The review of the factors affecting study heterogeneity and sample size indicated that as sample size increased, the prevalence of among children in Iran also increased ( = 0.578). Additionally, with an increase in the year of conducting the studies, the prevalence of among children in Iran decreased ( < 0.05).
The findings of this study show a relatively high prevalence of among children in Iran. We recommend health policymakers recognize the significance of this issue and take necessary measures to reduce the incidence of this infectious agent in children, implementing more effective preventive measures through mass media and educational campaigns.
寄生虫感染是全球最常见的疾病之一，蛲虫病是儿童中一种广为人知的寄生虫感染类型。鉴于伊朗不同省份有若干关于[具体寄生虫名称未给出]患病率的报告，且报告的患病率数据存在异质性，本研究旨在通过系统评价和荟萃分析调查伊朗儿童中[具体寄生虫名称未给出]的总体患病率。
这项系统评价和荟萃分析研究全面检索了多个数据库，包括PubMed、ScienceDirect、SID和谷歌学术，重点关注调查伊朗儿童[具体寄生虫名称未给出]感染患病率的横断面研究。将纳入的研究录入EndNote软件进行审查。使用STROBE清单评估观察性研究的质量。从研究中提取的信息录入综合荟萃分析（CMA，第2版）软件。使用I检验分析研究间的异质性，使用Egger检验和漏斗图评估发表偏倚。
本评价共纳入51项研究，样本量为46,070名儿童。采用随机效应模型，确定伊朗儿童中[具体寄生虫名称未给出]的总体患病率为6.7%（95%CI：5.2 - 8.6）。对影响研究异质性和样本量的因素进行审查表明，随着样本量增加，伊朗儿童中[具体寄生虫名称未给出]的患病率也增加（[相关系数值未给出] = 0.578）。此外，随着研究开展年份的增加，伊朗儿童中[具体寄生虫名称未给出]的患病率下降（[相关系数值未给出]<0.05）。
本研究结果显示伊朗儿童中[具体寄生虫名称未给出]的患病率相对较高。我们建议卫生政策制定者认识到这一问题的重要性，并采取必要措施降低儿童中这种传染源的发病率，通过大众媒体和教育活动实施更有效的预防措施。
