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海洋藻类的毒理学效应:人类食用需谨慎。

Toxicological effects of marine seaweeds: a cautious insight for human consumption.

机构信息

Shobhaben Pratapbhai Patel School of Pharmacy and Technology Management, SVKM's NMIMS, Mumbai, India.

出版信息

Crit Rev Food Sci Nutr. 2021;61(3):500-521. doi: 10.1080/10408398.2020.1738334. Epub 2020 Mar 19.

DOI:10.1080/10408398.2020.1738334
PMID:32188262
Abstract

Marine environment is a rich and diverse source for many biologically active substances including functional foods and nutraceuticals. It is well exploited for useful compounds, natural products and aquaculture industry; and seaweeds is one of the major contributors in terms of both food security and healthy nutrition. They are well-known due to their enormous benefits and is consumed globally in many countries. However, there is lack of attention toward their toxicity reports which might be due toxic chemical compounds from seaweed, epiphytic bacteria or harmful algal bloom and absorbed heavy metals from seawater. The excess of these components might lead to harmful interactions with drugs and hormone levels in the human body. Due to their global consumption and to meet increasing demands, it is necessary to address their hazardous and toxic aspects. In this review, we have done extensive literature for healthy seaweeds, their nutritional composition while summarizing the toxic effects of selected seaweeds from red, brown and green group which includes- , , , , and sp, a microalgae (cyanobacteria) biomass is also included in toxicity discussion as it an important food supplement and many times shows adverse reactions and drug interactions. The identified compounds from seaweeds were concluded to be toxic to humans, though they exhibited certain beneficial effects too. They have an easy access in food chain and thus invade the higher trophic level organisms. This review will create an awareness among scientific and nonscientific community, as well as government organization to regulate edible seaweed consumption and keep them under surveillance for their beneficial and safe consumption.

摘要

海洋环境是许多具有生物活性的物质的丰富多样的来源,包括功能性食品和营养保健品。它被广泛开发利用于有用的化合物、天然产物和水产养殖业;海藻是食品保障和健康营养方面的主要贡献者之一。由于其巨大的益处,海藻在许多国家都被广泛食用。然而,人们对它们的毒性报告关注甚少,这可能是由于海藻、附生细菌或有害藻类水华中的有毒化学化合物以及从海水中吸收的重金属。这些成分的过量可能会导致与人体药物和激素水平的有害相互作用。由于海藻的全球消费以及满足不断增长的需求,有必要解决它们的危险和毒性方面的问题。在这篇综述中,我们广泛查阅了健康海藻的文献,总结了红藻、褐藻和绿藻组中选定海藻的毒性作用,其中包括、、、、和,微藻(蓝藻)生物质也包括在毒性讨论中,因为它是一种重要的食品补充剂,而且很多时候会表现出不良反应和药物相互作用。从海藻中鉴定出的化合物对人类有毒,但它们也表现出某些有益的作用。它们在食物链中很容易获得,因此会侵入更高营养级的生物。本综述将提高科学界和非科学界以及政府组织的认识,规范可食用海藻的消费,并对其进行有益和安全消费的监测。

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