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胚胎学研究在唇裂畸形外科治疗中的重要性。

The importance of embryological research in the surgical management of the cleft lip deformity.

作者信息

Green M F

机构信息

Welsh Centre for Burns Plastic and Maxillofacial Surgery, St. Lawrence Hospital, Chepstow, Gwent, Wales, U.K.

出版信息

Ann Acad Med Singap. 1988 Jul;17(3):315-8.

PMID:3218920
Abstract

The cleft lip deformity has been present throughout mankind, and has entered into the folklore of Nations. There has been a multitude of described repairs. Still they do not provide the hoped for final results. Some of the changes have been based on "thought out" ideas, others on futile guesses. The last few years have seen changes in the surgical direction due to a clearer understanding of the basic embryology. These changes have been made possible by advances in equipment and technology. Changes in animal research, both intra- and extra-uterine, have made possible experiments which may answer some of the suppositions put forward covering both development and healing. The classification of cleft lip places all the deformities in one group, but there may in fact be several groups with different actual causes and failures leading to the same clinical picture. The understanding of the failure or failures that occur in development should lead to a logical approach to the repair of the cleft deformity.

摘要

唇裂畸形在全人类中一直存在,并已融入各国的民间传说。已经有大量描述的修复方法。然而,它们仍未提供人们所期望的最终效果。有些改变是基于“深思熟虑”的想法,其他的则是基于徒劳的猜测。在过去几年里,由于对基本胚胎学有了更清晰的认识,手术方向发生了变化。设备和技术的进步使这些变化成为可能。子宫内和子宫外动物研究的变化使得一些实验成为可能,这些实验可能会解答一些关于发育和愈合的假设。唇裂的分类将所有畸形归为一组,但实际上可能有几组不同的实际病因和导致相同临床表现的失败原因。对发育过程中出现的一个或多个失败原因的理解应该会引导出一种合理的唇裂畸形修复方法。

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1
The importance of embryological research in the surgical management of the cleft lip deformity.胚胎学研究在唇裂畸形外科治疗中的重要性。
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