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哮喘、长期哮喘控制药物治疗与美国青少年和年轻成年人的牙齿磨损

Asthma, long-term asthma control medication and tooth wear in American adolescents and young adults.

机构信息

Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, London, UK.

出版信息

J Asthma. 2021 Jul;58(7):939-945. doi: 10.1080/02770903.2020.1745228. Epub 2020 Apr 2.

DOI:10.1080/02770903.2020.1745228
PMID:32189532
Abstract

OBJECTIVE

This study explored the associations of asthma and long-term asthma control medication with tooth wear among American adolescents and young adults.

METHODS

Data from 2186 participants of the National Health and Nutrition Examination Survey (NHANES) were used. Asthma and prescribed long-term medication were collected through questionnaires. The number of surfaces with tooth wear was determined during clinical examinations. Associations were tested in Hurdle regression models adjusting for confounders.

RESULTS

The prevalence of tooth wear was 58%, with an average of 6.1 (SD: 4.0) surfaces affected among those with the condition. The prevalence of asthma was 10.3%, with 2.9% of participants using long-term medication for asthma control. In the adjusted regression model, asthma was not associated with tooth wear. However, long-term control medication was associated with greater odds of having tooth wear (odds ratio: 3.33; 95%CI: 1.24-8.97), but it was not associated with the number of surfaces with tooth wear among those with the condition (rate ratio: 1.01; 95% CI: 0.58-1.75).

CONCLUSION

This cross-sectional analysis of national data shows that taking long-term asthma medication was positively associated with having tooth wear.

摘要

目的

本研究探讨了哮喘和长期哮喘控制药物与美国青少年和年轻人牙齿磨损之间的关系。

方法

使用了来自国家健康和营养检查调查(NHANES)的 2186 名参与者的数据。通过问卷调查收集哮喘和规定的长期药物使用情况。在临床检查中确定牙齿磨损的表面数量。在调整混杂因素的障碍回归模型中测试关联。

结果

牙齿磨损的患病率为 58%,其中患有该疾病的患者平均有 6.1(SD:4.0)个表面受到影响。哮喘的患病率为 10.3%,有 2.9%的参与者使用长期药物控制哮喘。在调整后的回归模型中,哮喘与牙齿磨损无关。然而,长期控制药物与牙齿磨损的可能性更大相关(比值比:3.33;95%CI:1.24-8.97),但与患有该疾病的患者的牙齿磨损表面数量无关(比率比:1.01;95%CI:0.58-1.75)。

结论

这项基于全国数据的横断面分析表明,长期使用哮喘药物与牙齿磨损呈正相关。

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