Mohanty Aishwariya, Mishra Pallavi, Kumar Harish, Panda Abikshyeet
Department of Oral and Maxillofacial Pathology and Oral Microbiology, Kalinga Institute of Dental Sciences, Bhubaneswar, Odisha, India.
J Oral Maxillofac Pathol. 2020 Feb;24(Suppl 1):S73-S76. doi: 10.4103/jomfp.JOMFP_321_19. Epub 2020 Feb 28.
Fibrous histiocytoma is a soft-tissue tumor that may present as a fibrous mass anywhere in the human body. The involvement of the oral cavity is rare. We here report a case of benign fibrous histiocytoma localized in the maxilla. A 25-year-old male presented with a slowly increasing large painless mass over the left side of the upper jaw for 5 months. The swelling was of gradual onset, slowly progressive and was not associated with pain, tenderness, or discharge. The radiographic appearance showed a multilocular mixed radiodense, radiolucent lesion in the left posterior maxilla. The histopathological report showed connective tissue component having streaming fascicles of spindle-shaped cells showing a storiform pattern. Many areas showed foamy histiocytes along with few multinucleated giant cells. The cells were appearing benign without any appearance of atypia. The tumor cells were positive for CD-68 and vimentin and negative for CD-34 and S100. The lesion was excised under general anesthesia.
纤维组织细胞瘤是一种软组织肿瘤，可表现为人体任何部位的纤维性肿块。口腔受累较为罕见。我们在此报告一例位于上颌骨的良性纤维组织细胞瘤病例。一名25岁男性，左上颌左侧出现一个缓慢增大的无痛性肿块，持续5个月。肿胀起病缓慢，进展缓慢，与疼痛、压痛或分泌物无关。影像学表现显示左上颌后份有一个多房性混合性高密度、低密度病变。组织病理学报告显示结缔组织成分有梭形细胞的束状排列，呈车辐状图案。许多区域可见泡沫状组织细胞以及少量多核巨细胞。细胞呈良性，无任何异型性表现。肿瘤细胞CD-68和波形蛋白呈阳性，CD-34和S-100呈阴性。病变在全身麻醉下切除。
