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上颌骨良性纤维组织细胞瘤的罕见表现。

A rare presentation of benign fibrous histiocytoma in the maxilla.

作者信息

Mohanty Aishwariya, Mishra Pallavi, Kumar Harish, Panda Abikshyeet

机构信息

Department of Oral and Maxillofacial Pathology and Oral Microbiology, Kalinga Institute of Dental Sciences, Bhubaneswar, Odisha, India.

出版信息

J Oral Maxillofac Pathol. 2020 Feb;24(Suppl 1):S73-S76. doi: 10.4103/jomfp.JOMFP_321_19. Epub 2020 Feb 28.

Abstract

Fibrous histiocytoma is a soft-tissue tumor that may present as a fibrous mass anywhere in the human body. The involvement of the oral cavity is rare. We here report a case of benign fibrous histiocytoma localized in the maxilla. A 25-year-old male presented with a slowly increasing large painless mass over the left side of the upper jaw for 5 months. The swelling was of gradual onset, slowly progressive and was not associated with pain, tenderness, or discharge. The radiographic appearance showed a multilocular mixed radiodense, radiolucent lesion in the left posterior maxilla. The histopathological report showed connective tissue component having streaming fascicles of spindle-shaped cells showing a storiform pattern. Many areas showed foamy histiocytes along with few multinucleated giant cells. The cells were appearing benign without any appearance of atypia. The tumor cells were positive for CD-68 and vimentin and negative for CD-34 and S100. The lesion was excised under general anesthesia.

摘要

纤维组织细胞瘤是一种软组织肿瘤,可表现为人体任何部位的纤维性肿块。口腔受累较为罕见。我们在此报告一例位于上颌骨的良性纤维组织细胞瘤病例。一名25岁男性,左上颌左侧出现一个缓慢增大的无痛性肿块,持续5个月。肿胀起病缓慢,进展缓慢,与疼痛、压痛或分泌物无关。影像学表现显示左上颌后份有一个多房性混合性高密度、低密度病变。组织病理学报告显示结缔组织成分有梭形细胞的束状排列,呈车辐状图案。许多区域可见泡沫状组织细胞以及少量多核巨细胞。细胞呈良性,无任何异型性表现。肿瘤细胞CD-68和波形蛋白呈阳性,CD-34和S-100呈阴性。病变在全身麻醉下切除。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d16/7069126/048c8a67da75/JOMFP-24-73-g001.jpg

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