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口腔恶性黑色素瘤

Oral malignant melanoma.

作者信息

Ashok Sahana, Damera Srikanth, Ganesh Siva, Karri Rojalakshmi

机构信息

Department of Oral and Maxillofacial Pathology, GSL Dental College, Rajahmundry, Andhra Pradesh, India.

Department of Oral Surgery, GSL Dental College, Rajahmundry, Andhra Pradesh, India.

出版信息

J Oral Maxillofac Pathol. 2020 Feb;24(Suppl 1):S82-S85. doi: 10.4103/jomfp.JOMFP_5_19. Epub 2020 Feb 28.

Abstract

Malignant melanoma in the head and neck area is rare. The incidence of oral malignant melanomas of the head and neck is approximately four per 10 million populations per year. They are derived from epidermal melanocytes and are most frequently seen on the palate and maxillary gingiva. They are asymptomatic initially but become painful with progress and enlargement. Later, they are associated with ulceration, bleeding, mobility of tooth, paresthesia and ill-fitting prosthesis. The diagnosis is often delayed due to silent growth and development of the lesion. Oral malignant melanomas are associated with poor prognosis due to their invasive and metastasizing tendencies. This case report is presented to emphasize the role of a dentist in identifying the pigmented lesions of the oral cavity.

摘要

头颈部恶性黑色素瘤较为罕见。头颈部口腔恶性黑色素瘤的发病率约为每年每1000万人口中有4例。它们起源于表皮黑素细胞,最常见于腭部和上颌牙龈。起初它们没有症状,但随着病情进展和肿瘤增大,会变得疼痛。随后,它们会出现溃疡、出血、牙齿松动、感觉异常和义齿不合适等症状。由于病变生长和发展隐匿,诊断往往会延迟。口腔恶性黑色素瘤因其侵袭性和转移倾向,预后较差。本病例报告旨在强调牙医在识别口腔色素沉着病变中的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c30/7069155/f0f48227d0b0/JOMFP-24-82-g001.jpg

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