• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

口腔恶性黑色素瘤

Oral malignant melanoma.

作者信息

Ashok Sahana, Damera Srikanth, Ganesh Siva, Karri Rojalakshmi

机构信息

Department of Oral and Maxillofacial Pathology, GSL Dental College, Rajahmundry, Andhra Pradesh, India.

Department of Oral Surgery, GSL Dental College, Rajahmundry, Andhra Pradesh, India.

出版信息

J Oral Maxillofac Pathol. 2020 Feb;24(Suppl 1):S82-S85. doi: 10.4103/jomfp.JOMFP_5_19. Epub 2020 Feb 28.

DOI:10.4103/jomfp.JOMFP_5_19
PMID:32189911
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7069155/
Abstract

Malignant melanoma in the head and neck area is rare. The incidence of oral malignant melanomas of the head and neck is approximately four per 10 million populations per year. They are derived from epidermal melanocytes and are most frequently seen on the palate and maxillary gingiva. They are asymptomatic initially but become painful with progress and enlargement. Later, they are associated with ulceration, bleeding, mobility of tooth, paresthesia and ill-fitting prosthesis. The diagnosis is often delayed due to silent growth and development of the lesion. Oral malignant melanomas are associated with poor prognosis due to their invasive and metastasizing tendencies. This case report is presented to emphasize the role of a dentist in identifying the pigmented lesions of the oral cavity.

摘要

头颈部恶性黑色素瘤较为罕见。头颈部口腔恶性黑色素瘤的发病率约为每年每1000万人口中有4例。它们起源于表皮黑素细胞,最常见于腭部和上颌牙龈。起初它们没有症状,但随着病情进展和肿瘤增大,会变得疼痛。随后,它们会出现溃疡、出血、牙齿松动、感觉异常和义齿不合适等症状。由于病变生长和发展隐匿,诊断往往会延迟。口腔恶性黑色素瘤因其侵袭性和转移倾向,预后较差。本病例报告旨在强调牙医在识别口腔色素沉着病变中的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c30/7069155/a7ccabb7f145/JOMFP-24-82-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c30/7069155/f0f48227d0b0/JOMFP-24-82-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c30/7069155/537b4499de81/JOMFP-24-82-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c30/7069155/a7ccabb7f145/JOMFP-24-82-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c30/7069155/f0f48227d0b0/JOMFP-24-82-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c30/7069155/537b4499de81/JOMFP-24-82-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c30/7069155/a7ccabb7f145/JOMFP-24-82-g003.jpg

相似文献

1
Oral malignant melanoma.口腔恶性黑色素瘤
J Oral Maxillofac Pathol. 2020 Feb;24(Suppl 1):S82-S85. doi: 10.4103/jomfp.JOMFP_5_19. Epub 2020 Feb 28.
2
Oral malignant melanoma: An aggressive clinical entity - Report of a rare case with review of literature.口腔恶性黑色素瘤:一种侵袭性临床实体——1例罕见病例报告并文献复习
J Int Soc Prev Community Dent. 2016 Mar-Apr;6(2):176-81. doi: 10.4103/2231-0762.175145.
3
Malignant melanoma of the oral cavity: Report of two cases.口腔恶性黑色素瘤:两例报告。
Contemp Clin Dent. 2014 Apr;5(2):227-30. doi: 10.4103/0976-237X.132352.
4
Oral malignant melanoma - Clinical presentation with immunohistochemical analysis.口腔恶性黑色素瘤——临床表现及免疫组化分析
J Cancer Res Ther. 2023 Jan 1;19(Suppl 2):S935-S938. doi: 10.4103/jcrt.jcrt_1364_22. Epub 2023 Apr 28.
5
Rare and Extensive Malignant Melanoma of the Oral Cavity: Report of Two Cases.口腔罕见广泛性恶性黑色素瘤:两例报告
J Dent (Shiraz). 2017 Sep;18(3):227-233.
6
Primary oral malignant melanoma--a case report and review of the literature.原发性口腔恶性黑色素瘤——病例报告及文献综述
Quintessence Int. 2009 Jan;40(1):41-46. doi: 10.3290/j.qi.a14113.
7
Malignant melanoma of the oral cavity.口腔恶性黑色素瘤
Indian J Dent Res. 2006 Apr-Jun;17(2):94-6. doi: 10.4103/0970-9290.29882.
8
A Case Report of Oral Malignant Melanoma: A Silent Killer.口腔恶性黑色素瘤病例报告:隐匿的杀手
Cureus. 2023 Mar 25;15(3):e36671. doi: 10.7759/cureus.36671. eCollection 2023 Mar.
9
Malignant melanoma of gingiva: Report of a rare case.牙龈恶性黑色素瘤:1例罕见病例报告。
Indian J Dent. 2015 Jul-Sep;6(3):161-4. doi: 10.4103/0975-962X.163052.
10
Oral malignant melanoma: A case report with review of literature.口腔恶性黑色素瘤:一例病例报告并文献复习
Contemp Clin Dent. 2014 Jul;5(3):415-8. doi: 10.4103/0976-237X.137978.

引用本文的文献

1
Primary Malignant Melanoma of the Oropharynx: A Rare Case of a Tonsillar Melanotic Lesion.口咽原发性恶性黑色素瘤:一例罕见的扁桃体黑色素病变病例
Cureus. 2025 Apr 20;17(4):e82637. doi: 10.7759/cureus.82637. eCollection 2025 Apr.
2
Mucosal melanoma of hard palate.硬腭黏膜黑色素瘤
Autops Case Rep. 2024 Nov 14;14:e2024522. doi: 10.4322/acr.2024.522. eCollection 2024.
3
Oral malignant melanoma of the lower jaw-a case report with immunohistochemical investigations.下颌部口腔恶性黑色素瘤——一例免疫组化研究病例报告

本文引用的文献

1
Oral malignant melanoma: An aggressive clinical entity - Report of a rare case with review of literature.口腔恶性黑色素瘤:一种侵袭性临床实体——1例罕见病例报告并文献复习
J Int Soc Prev Community Dent. 2016 Mar-Apr;6(2):176-81. doi: 10.4103/2231-0762.175145.
2
Melanoma of the oral cavity: pathogenesis, dermoscopy, clinical features, staging and management.口腔黑色素瘤:发病机制、皮肤镜检查、临床特征、分期及治疗
J Dermatol Case Rep. 2014 Sep 30;8(3):60-6. doi: 10.3315/jdcr.2014.1175.
3
Intraoral malignant melanoma.口腔内恶性黑色素瘤。
Ecancermedicalscience. 2023 Jun 15;17:1561. doi: 10.3332/ecancer.2023.1561. eCollection 2023.
4
PReferentially Expressed Antigen in MElanoma (PRAME): preliminary communication on a translational tool able to early detect Oral Malignant Melanoma (OMM).黑色素瘤中优先表达的抗原(PRAME):关于一种能够早期检测口腔恶性黑色素瘤(OMM)的转化工具的初步通讯
J Cancer. 2023 Feb 27;14(4):628-633. doi: 10.7150/jca.82389. eCollection 2023.
5
lncRNA AGAP2-AS1 Facilitates Tumorigenesis and Ferroptosis Resistance through SLC7A11 by IGF2BP2 Pathway in Melanoma.lncRNA AGAP2-AS1 通过 IGF2BP2 通路调控 SLC7A11 促进黑色素瘤的发生发展及耐药性
Comput Math Methods Med. 2022 Jun 6;2022:1972516. doi: 10.1155/2022/1972516. eCollection 2022.
6
Oral malignant melanoma: a rarity!口腔恶性黑色素瘤:罕见!
BMJ Case Rep. 2021 Nov 11;14(11):e246045. doi: 10.1136/bcr-2021-246045.
7
Treatment Modalities of Recurrent Oral Mucosal Melanoma In Situ.复发性口腔黏膜原位黑色素瘤的治疗方式。
Medicina (Kaunas). 2021 Sep 14;57(9):965. doi: 10.3390/medicina57090965.
Niger Med J. 2013 Jul;54(4):278-81. doi: 10.4103/0300-1652.119667.
4
Primary oral malignant melanoma: two case reports and review of literature.原发性口腔恶性黑色素瘤:两例病例报告及文献综述
Case Rep Dent. 2012;2012:975358. doi: 10.1155/2012/975358. Epub 2012 Jul 30.
5
Oral malignant melanoma: a review of the literature.口腔恶性黑色素瘤:文献综述
J Oral Pathol Med. 2008 Aug;37(7):383-8. doi: 10.1111/j.1600-0714.2008.00660.x. Epub 2008 Feb 17.
6
Malignant melanoma of the oral cavity: a review of literature.口腔恶性黑色素瘤:文献综述
Indian J Dent Res. 2008 Jan-Mar;19(1):47-51. doi: 10.4103/0970-9290.38932.
7
Oral mucosal melanoma: a malignant trap.口腔黏膜黑色素瘤:一个恶性陷阱。
Head Face Med. 2006 Mar 28;2:7. doi: 10.1186/1746-160X-2-7.
8
A practical method for clinical diagnosis of oral mucosal melanomas.一种用于口腔黏膜黑色素瘤临床诊断的实用方法。
Med Oral. 2003 Nov-Dec;8(5):348-52.
9
Primary malignant melanoma of the oral cavity: a review of 105 cases.口腔原发性恶性黑色素瘤:105例病例回顾
Cancer. 1958 Sep-Oct;11(5):923-8. doi: 10.1002/1097-0142(195809/10)11:5<923::aid-cncr2820110507>3.0.co;2-1.
10
Surgical margins for excision of primary cutaneous melanoma.原发性皮肤黑色素瘤切除的手术切缘
J Am Acad Dermatol. 1997 Sep;37(3 Pt 1):422-9. doi: 10.1016/s0190-9622(97)70144-0.